Results 11 to 20 of about 167,546 (223)

Cleaving Ergot Alkaloids by Hydrazinolysis—A Promising Approach for a Sum Parameter Screening Method

open access: yesToxins, 2021
Ergot alkaloids are mycotoxins formed by fungi of the Claviceps genus, which are some of the most common contaminants of food and feed worldwide. These toxins are a structurally heterogeneous group of compounds, sharing an ergoline backbone.
Maximilian Kuner   +4 more
doaj   +2 more sources

Activities and Effects of Ergot Alkaloids on Livestock Physiology and Production [PDF]

open access: goldToxins, 2015
Consumption of feedstuffs contaminated with ergot alkaloids has a broad impact on many different physiological mechanisms that alters the homeostasis of livestock.
James L. Klotz
doaj   +3 more sources

Validation of a New Sensitive Method for the Detection and Quantification of R and S-Epimers of Ergot Alkaloids in Canadian Spring Wheat Utilizing Deuterated Lysergic Acid Diethylamide as an Internal Standard

open access: yesToxins, 2021
Ergot sclerotia effect cereal crops intended for consumption. Ergot alkaloids within ergot sclerotia are assessed to ensure contamination is below safety standards established for human and animal health.
Jensen Cherewyk   +3 more
doaj   +2 more sources

Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems

open access: yesBiomolecules, 2020
Several pharmacological properties are attributed to ergot alkaloids as a result of their antibacterial, antiproliferative, and antioxidant effects.
Iara Baldim   +12 more
doaj   +2 more sources

Fate of Ergot Alkaloids during Laboratory Scale Durum Processing and Pasta Production

open access: yesToxins, 2019
The fate of ergot alkaloids during the milling of durum and subsequent production and cooking of pasta was examined. Durum samples containing varying amounts of ergot sclerotia (0.01–0.1% by mass) were milled, and all milling product was analyzed ...
Sheryl A. Tittlemier   +5 more
doaj   +2 more sources

Albert Hofmann's Pioneering Work on Ergot Alkaloids and Its Impact on the Search of Novel Drugs at Sandoz, a Predecessor Company of Novartis: Dedicated to Dr. Albert Hofmann on the occasion of his 100th birthday

open access: diamondCHIMIA, 2006
The scientific research on ergot alkaloids is fundamentally related to the work of Dr. Albert Hofmann, who was able to produce, from 1935 onwards, a number of novel and valuable drugs, some of which are still in use today.
Rudolf K.A. Giger, Günter Engel
doaj   +3 more sources

Ergot alkaloids contribute to virulence in an insect model of invasive aspergillosis

open access: yesScientific Reports, 2017
Neosartorya fumigata (Aspergillus fumigatus) is the most common cause of invasive aspergillosis, a frequently fatal lung disease primarily affecting immunocompromised individuals. This opportunistic fungal pathogen produces several classes of specialised
Daniel G. Panaccione   +1 more
doaj   +2 more sources

Epimerization of ergot alkaloids in feed

open access: yesHeliyon, 2020
Chronic intake of cereals contaminated with ergot alkaloids can cause ergotism and result in the loss of toes and fingers or even death. Today, due to common risk management practices, ergotism is rare as a human disease but remains a problem in ...
Claude Schummer   +3 more
doaj   +2 more sources

Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species

open access: yesToxins, 2019
Fescue toxicosis is a multifaceted syndrome that elicits many negative effects on livestock consuming ergot alkaloids produced by endophyte-infected tall fescue.
Rebecca K. Poole, Daniel H. Poole
doaj   +2 more sources

Application of Liquid Chromatography/Ion Trap Mass Spectrometry Technique to Determine Ergot Alkaloids in Grain Products

open access: diamondFood Technology and Biotechnology, 2015
A liquid chromatography/ion trap mass spectrometry-based method to determine six ergot alkaloids and their isomers is presented. The samples were cleaned on neutral alumina-based solid-phase extraction cartridges.
Marcin Bryła   +3 more
doaj   +2 more sources

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