Results 181 to 190 of about 254,157 (265)

Combined Inhibition of HRAS and MEK Induces Tumor Regression and Restores Myogenic Differentiation in HRAS-Mutant Rhabdomyosarcoma. [PDF]

Cancer Res
Odeniyide P, Skaist A, Fenner E, Amirkhanian H, Baker A, Lisok A, Zhang L, Fridman LB, Rojas RI, Hebron KE, Davis C, Zhang X, Feldman G, Angus SP, Thomas CJ, Vaseva AV, Yohe ME, Fertig EJ, Pratilas CA.   +18 more
europepmc   +1 more source

Refining the Role of ERK Signaling in Anthracycline-Induced Cardiotoxicity. [PDF]

JACC CardioOncol
Wang Z, Zhao D.
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Insulin increases expression of cannabinoid receptor 1 by suppressing lysosomal degradation via ERK signaling pathway. [PDF]

Int J Med Sci
Liu SY, Ting CH, Hwang GS, Chen CW, Chen LK, Ho PH, Lee PH, Wu GL, Yin WH, Wu LY, Seow KM, Lin HF, Juan CC.   +12 more
europepmc   +1 more source

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

iLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang, Jia Liu, Chengrong Bian, Wenwen Yuan, Wang Zhang, Fan Feng, Boan Li   +6 more
wiley   +1 more source

Hierarchical Disruption of the Tryptophan-Melatonin Axis Contributes to Glioma Progression Through AKT/ERK/STAT3 Signalling. [PDF]

J Cell Mol Med
Tan B, Yao S, He S, Chen T, Chen H, Yang W, Tang X, Xu T, Zhang J, Yin X, Chen Y, Song P.   +11 more
europepmc   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

EPHB2 drives EMT-linked vasculogenic mimicry and cervical cancer progression via an ERK-ETV4 transcriptional program. [PDF]

J Transl Med
Jiao W, Liu S, Huai Q, Zhang Z, He Q, Yang X, Yu M.   +6 more
europepmc   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

iMetaOmics, EarlyView.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou, Cheng Guo, Mahmoud M. Abdelsattar, Ahmad R. Musa, Mequanint Biks, Abdullahi A. Musa, Shahnaz Rahman, Abera Teshome Aleli, Pei Zhong, Jiawei Zhang, Junwei Cui, Xiyan Kou, Qingyuan Yu, Caijuan Yue, Qin Li, Dan Zhang, Zixuan Peng, Ao Ren, Ziqi Tian, Ziqi Liu, Yaona Zhang, Lili Zhang, Dina Karmallah, Naifeng Zhang, Tao Ma, Yan Tu, Qiyu Diao, Guijie Zhang, Xiaofeng Xu, Yanliang Bi   +29 more
wiley   +1 more source

IGF-1 Stereotaxic Injection Induces BDNF Expression After Bilateral Common Carotid Artery Occlusion. [PDF]

In Vivo
Park J, Hwang H, Shin H, Chung Y, Kim D, Jun Y.   +5 more
europepmc   +1 more source