Results 201 to 210 of about 254,157 (265)

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

Effects of Electroacupuncture on Knee Osteoarthritis in Rats Through Suppressing p38 MAPK/ERK/CREB Pathway. [PDF]

J Inflamm Res
Wang J, Wang F, Guo Y, Liu T, Li J, Zou J, Luan F, Gao T, Wang W.   +8 more
europepmc   +1 more source

mTORC1 and nuclear ERK spatially control translation in cardiomyocytes through 4EBP1 phosphorylation. [PDF]

Sci Signal
Uchida K, Scarborough EA, Pruzinsky E, Stone KR, Hartman H, Kelly DP, Edwards JJ, Kehat I, Prosser BL.   +8 more
europepmc   +1 more source

Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases. [PDF]

Parasite Immunol
Ribeiro FN, Morgado FN, Porrozzi R.
europepmc   +1 more source

Structure-Based Virtual Screening and Mechanistic Characterization of Methotrexate and Selinexor as Potent Anti-Melanogenic Agents via Multi-Pathway Suppression of MITF. [PDF]

Cells
Zhang Z, Li H, Shi Z, Bai X, Yin P, Yang L.   +5 more
europepmc   +1 more source

Docosahexaenoic Acid Attenuates Visceral Pain by Suppressing Spinal CXCL10/CXCR3/ERK Signaling. [PDF]

Nutrients
Yin X, Jiang A, Han Y, Qu J, Zhao J, Gong H, Luo X, Li X, Lu Y.   +8 more
europepmc   +1 more source

Chromatin remodelling enables enhancer resetting to facilitate the ERK transcriptional response

Ragheb R, Reynolds N, Shah D, Lopez M, Balmer J, Markozanis N, Gade P, Koulle A, Ogundele O, Floyd R, Laue E, Hendrich B.   +11 more
europepmc   +1 more source