Results 161 to 170 of about 10,382 (181)
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ESCRT-III polymers in membrane neck constriction
Trends in Cell Biology, 2012The endosomal sorting complex required for transport (ESCRT)-III machinery contributes to membrane deformation and scission in cytokinesis, intraluminal vesicle formation, autophagy and virus budding. Recombinant ESCRT-III subunits polymerize in vitro into filaments, tubes, sheets or rings, and ESCRT-III-dependent filaments have been observed in cells ...
Guizetti J, Gerlich DW
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AbstractMitochondria play important roles in energy generation and homeostasis maintenance in eukaryotic cells. The damaged or superfluous mitochondria can be nonselectively or selectively removed through the autophagy/lysosome pathway, which was referred as mitophagy.
Zulin Wu +4 more
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Fine-tuning pyroptosis with ESCRT-III
Science, 2018Immunology Pyroptosis is an inflammatory form of cell death induced by select caspases downstream of inflammasome complexes. These caspases cleave gasdermin D (GSDMD), whose N-terminal fragments quickly form large permeability pores that induce cell death. However, a large percentage of cells with active inflammasomes are resistant to pyroptosis.
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Interactions in the ESCRT-III network of the yeast Saccharomyces cerevisiae
Current Genetics, 2018Here, we examine the genetic interactions between ESCRT-III mutations in the yeast Saccharomyces cerevisiae. From the obtained interaction network, we make predictions about alternative ESCRT-III complexes. By the successful generation of an octuple deletion strain using the CRISPR/Cas9 technique, we demonstrate for the first time that ESCRT-III ...
Thomas Brune +2 more
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PspA adopts an ESCRT-III-like fold and remodels bacterial membranes
Cell, 2021Benedikt Junglas +2 more
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Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily
Cell, 2021Matteo Tassinari +2 more
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An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission
Cell, 2020Xiuyun Jiang +2 more
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ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
Cell, 2017Andreas Linkermann +2 more
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Membrane budding and scission by the ESCRT machinery: it's all in the neck
Nature Reviews Molecular Cell Biology, 2010James Hurley +2 more
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Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes
Annual Review of Cell and Developmental Biology, 2018John Mccullough +2 more
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