Results 1 to 10 of about 26,768 (226)
Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10 [PDF]
Nature Communications, 2021 Salmonella secretes the effector protein SopD into the host cell cytoplasm, leading to scission of the plasma membrane through unclear mechanisms. Here, Boddy et al.
Kirsten C. Boddy +11 more
doaj +9 more sources
Timing of ESCRT-III protein recruitment and membrane scission during HIV-1 assembly [PDF]
eLife, 2018 The Endosomal Sorting Complexes Required for Transport III (ESCRT-III) proteins are critical for cellular membrane scission processes with topologies inverted relative to clathrin-mediated endocytosis.
Daniel S Johnson +2 more
doaj +2 more sources
The ESCRT Machinery: Remodeling, Repairing, and Sealing Membranes
Membranes, 2022 The ESCRT machinery is an evolutionarily conserved membrane remodeling complex that is used by the cell to perform reverse membrane scission in essential processes like protein degradation, cell division, and release of enveloped retroviruses. ESCRT-III,
Yolanda Olmos
doaj +1 more source
Domes and cones: Adhesion-induced fission of membranes by ESCRT proteins. [PDF]
PLoS Computational Biology, 2018 ESCRT proteins participate in the fission step of exocytic membrane budding, by assisting in the closure and scission of the membrane neck that connects the nascent bud to the plasma membrane.
Jaime Agudo-Canalejo, Reinhard Lipowsky
doaj +1 more source
Modelling membrane reshaping by staged polymerization of ESCRT-III filaments.
PLoS Computational Biology, 2022 ESCRT-III filaments are composite cytoskeletal polymers that can constrict and cut cell membranes from the inside of the membrane neck. Membrane-bound ESCRT-III filaments undergo a series of dramatic composition and geometry changes in the presence of an
Xiuyun Jiang +7 more
doaj +1 more source
A new role for myosin II in vesicle fission. [PDF]
PLoS ONE, 2014 An endocytic vesicle is formed from a flat plasma membrane patch by a sequential process of invagination, bud formation and fission. The scission step requires the formation of a tubular membrane neck (the fission pore) that connects the endocytic ...
Juan A Flores +5 more
doaj +1 more source
Viruses, 2021 The proper assembly and dissemination of progeny virions is a fundamental step in virus replication. As a whole, viruses have evolved a myriad of strategies to exploit cellular compartments and mechanisms to ensure a successful round of infection.
Kevin M. Rose +3 more
doaj +1 more source
Lipid accumulation controls the balance between surface connection and scission of caveolae
eLife, 2020 Caveolae are bulb-shaped invaginations of the plasma membrane (PM) that undergo scission and fusion at the cell surface and are enriched in specific lipids.
Madlen Hubert +6 more
doaj +1 more source
Insights into the function of ESCRT and its role in enveloped virus infection
Frontiers in Microbiology, 2023 The endosomal sorting complex required for transport (ESCRT) is an essential molecular machinery in eukaryotic cells that facilitates the invagination of endosomal membranes, leading to the formation of multivesicular bodies (MVBs).
Chunxuan Wang +5 more
doaj +1 more source
A feedback loop between dynamin and actin recruitment during clathrin-mediated endocytosis.
PLoS Biology, 2012 Clathrin-mediated endocytosis proceeds by a sequential series of reactions catalyzed by discrete sets of protein machinery. The final reaction in clathrin-mediated endocytosis is membrane scission, which is mediated by the large guanosine triophosphate ...
Marcus J Taylor +2 more
doaj +1 more source