Results 131 to 140 of about 33,348 (245)

Tissue‐Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri, Erez Eitan, Kenneth W. Witwer, Diane B. Re, Andrea A. Baccarelli, Haotian Wu   +5 more
wiley   +1 more source

"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]

, 2007
Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core   +1 more source

Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress [PDF]

, 2020
Moona Huttunen, Artur Yakimovich, Ian J. White, János Kriston-Vizi, Juan Martin‐Serrano, Wesley I. Sundquist, Jason Mercer   +6 more
openalex   +1 more source

ESCRTs got your Bac! [PDF]

, 2021
Raunaq A. Deo, William A. Prinz
openalex   +1 more source

Research Progress of Exosome‐Derived microRNA in Alcohol Use Disorders: A Critical Review

Addiction Biology, Volume 31, Issue 2, February 2026.
Exosome‐derived microRNAs represent stable and mechanistically active mediators of alcohol‐induced multi‐organ injury. This review summarizes how chronic alcohol exposure reshapes exosomal miRNA cargo across the liver, immune system, and brain, highlighting key miRNAs with diagnostic value and therapeutic potential.
Bo Zhang, Ting ting Xie, Qiang Ma, Ya ping Jiang, Yu mei Wang   +4 more
wiley   +1 more source

Clinical Validation of α‐Synuclein in Salivary Extracellular Vesicles as a Biomarker for Parkinson's Disease: A Longitudinal Study

European Journal of Neurology, Volume 33, Issue 2, February 2026.
Salivary Extracellular vesicles (SEVs) isolated from PD patients exhibit increased levels of both total (α‐SynTot) and oligomeric alpha‐synuclein (α‐SynOlig). In PD patients, SEVS‐α‐SynOlig levels correlate with cognitive decline (MMSE) and motor fluctuations (MDS‐UPDRS IV) and remain stable after 1 year follow‐up.
Antonia Gurgone, Vita Cardinale, Marta M. Tangari, Serena Budicin, Debora Comai, Claudia Ledda, Leonardo Lopiano, Giovanni Camussi, Maurizio Zibetti, Maurizio Giustetto   +9 more
wiley   +1 more source

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

eLife, 2017
The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers.
Manuel Alonso Y Adell, Simona M Migliano, Srigokul Upadhyayula, Yury S Bykov, Simon Sprenger, Mehrshad Pakdel, Georg F Vogel, Gloria Jih, Wesley Skillern, Reza Behrouzi, Markus Babst, Oliver Schmidt, Michael W Hess, John AG Briggs, Tomas Kirchhausen, David Teis   +15 more
doaj   +1 more source

Nature's lessons in design: nanomachines to scaffold, remodel and shape membrane compartments. [PDF]

, 2015
Compartmentalisation of cellular processes is fundamental to regulation of metabolism in Eukaryotic organisms and is primarily provided by membrane-bound organelles.
Achalkumar, Adell, Agromayor, Aimon, Alexa J. Cleasby, Angelova, Angelova, Apellaniz, Arriaga, Axelrod, Ayton, Bacia, Bagatolli, Barbara Ciani, Baumgart, Baumgart, Baumgart, Bayburt, Bayley, Beales, Beales, Beales, Benkoski, Bennett, Bergstrom, Bernchou, Bernchou, Betz, Bleicken, Boden, Boura, Boyle, Burns, Campillo, Carvalho, Cashikar, Castellana, Chan, Chen, Cho, Cho, Cho, Churchman, Ciani, Connell, Cremer, Cui, Dahlin, Das, Denisov, Diao, Durrieu, Eggeling, Elani, Elani, Epand, Fabrikant, Fletcher, Frolov, Fuertes, Girard, Goh, Goksu, Gordon, Gradišar, Harrison, Haswell, Haustein, Helfrich, Henriksen, Hiyama, Holthuis, Honigmann, Hurley, Härtel, Iwabuchi, Jena, Jeuken, Karamdad, Katayama, Kiessling, Korlach, Kozlov, Kozlov, Kraft, Lamblet, Langecker, Lata, Leduc, Lin, Lindau, Liu, Longo, Ly, Lyman, López-Montero, Maglia, Majd, Manley, Marsh, Marsh, Marsh, Marsh, Mart, Martens, Melikyan, Mercker, Monck, Montes, Moran-Mirabal, Nath, Nath, Neumann, Nourian, Olbrich, Osawa, Parasassi, Park, Parlati, Paul A. Beales, Pautot, Pautot, Pecreaux, Persson, Peterman, Przybylo, Rabe, Ramadurai, Ramakrishnan, Raschle, Rawicz, Richmond, Ritchie, Robson Marsden, Roux, Ruan, Rydell, Różycki, Saarikangas, Schoen, Schwille, Semrau, Serien, Shaklee, Shi, Shoemaker, Shum, Siegel, Simonsson, Simunovic, Sorre, Sorre, Sorre, Soumpasis, Stachowiak, Stachowiak, Stegmann, Studer, Suetsugu, Syeda, Szoka, Söllner, Takatsuki, Tanaka, Tanaka, Templer, Thomas, Thompson, Tian, Tonnesen, Troutier, Tsai, Tsurudome, Voeltz, Vogel, Wagner, Wang, Wang, Weber, Weidemann, Weinberger, Wetterau, Wieprecht, Wilson, Wollert, Wollert, Woodman, Woolfson, Worsfold, Xu, Yoon, Yu, Yu, Yuan, Zhang, Zhao, Zhu, Zick, Árnadóttir   +198 more
core   +2 more sources

Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu, Jianfeng Zhang, Na Xiong, Yixiao Ma, Lingling Yong, Huaxu Liu, Qin Guo   +6 more
wiley   +1 more source

The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus.

PLoS Pathogens, 2012
The cellular endosomal sorting complex required for transport (ESCRT) machinery participates in membrane scission and cytoplasmic budding of many RNA viruses. Here, we found that expression of dominant negative ESCRT proteins caused a blockade of Epstein-
Chung-Pei Lee, Po-Ting Liu, Hsiu-Ni Kung, Mei-Tzu Su, Huey-Huey Chua, Yu-Hsin Chang, Chou-Wei Chang, Ching-Hwa Tsai, Fu-Tong Liu, Mei-Ru Chen   +9 more
doaj   +1 more source