Results 41 to 50 of about 33,348 (245)
eLife, 2022 The 12 related human ESCRT-III proteins form filaments that constrict membranes and mediate fission, including during cytokinetic abscission. The C-terminal tails of polymerized ESCRT-III subunits also bind proteins that contain Microtubule-Interacting ...
Dawn M Wenzel +6 more
doaj +1 more source
ESCRT machinery plays a role in microautophagy in yeast
BMC Molecular and Cell Biology, 2020 Background Microautophagy, which degrades cargos by direct lysosomal/vacuolar engulfment of cytoplasmic cargos, is promoted after nutrient starvation and the inactivation of target of rapamycin complex 1 (TORC1) protein kinase.
Shamsul Morshed +2 more
doaj +1 more source
Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]
, 2018 Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J. +14 more
core +3 more sources
Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes. [PDF]
, 2020 The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-
Avilov, I. +6 more
core +1 more source
Multidimensional Analysis of CHMP Family Members in Hepatocellular Carcinoma
International Journal of General Medicine, 2022 Yu Guo,1 An Shang,1 Shuang Wang,2 Min Wang1 1Department of General Surgery, Jilin University Second Hospital, Changchun, Jilin, People’s Republic of China; 2Department of Dermatology, Jilin University Second Hospital, Changchun, Jilin, People’s Republic ...
Guo Y, Shang A, Wang S, Wang M
doaj
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM
Cell Reports, 2018 Summary: The ESCRT machinery mediates membrane fission in a variety of processes in cells. According to current models, ESCRT-III proteins drive membrane fission by assembling into helical filaments on membranes.
Inna Goliand +6 more
doaj +1 more source
Nature Communications, 2022 Pore-forming Gasdermin protein-induced pyroptosis in tumor cells promotes anti-tumor immune response through the release of pro-inflammatory cytokines and immunogenic substances after cell rupture.
Zhaoting Li +7 more
semanticscholar +1 more source
MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. [PDF]
PLoS ONE, 2007 After ligand binding and endocytosis, cell surface receptors can continue to signal from endosomal compartments until sequestered from the cytoplasm. An important mechanism for receptor downregulation in vivo is via the inward budding of receptors into ...
Anjon Audhya +3 more
doaj +1 more source
The multifaceted interactions between pathogens and host ESCRT machinery
PLoS Pathogens, 2023 The Endosomal Sorting Complex Required for Transport (ESCRT) machinery consists of multiple protein complexes that coordinate vesicle budding away from the host cytosol.
Yolanda Rivera-Cuevas, V. Carruthers
semanticscholar +1 more source
Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]
, 2017 The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino +1 more
core +4 more sources