Results 51 to 60 of about 33,348 (245)

ESCRT Requirements for Murine Leukemia Virus Release

Viruses, 2016
The Murine Leukemia Virus (MLV) is a gammaretrovirus that hijack host components of the endosomal sorting complex required for transport (ESCRT) for budding.
Christina Bartusch, Reinhild Prange
doaj   +1 more source

Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

PLoS Pathogens, 2023
Extracellular vesicles (EVs) provide a central mechanism of cell–cell communication. While EVs are found in most organisms, their pathogenesis-promoting roles in parasites are of particular interest given the potential for medical insight and ...
Abel Cruz Camacho, Daniel Alfandari, E. Kozela, Neta Regev-Rudzki   +3 more
semanticscholar   +1 more source

Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]

, 2014
microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei, Kim, Yun Ju, Maizel, Alexis   +2 more
core   +3 more sources

Protein-protein interaction network and subcellular localization of the Arabidopsis thaliana ESCRT machinery

Frontiers in Plant Science, 2011
The Endosomal Sorting Complex Required for Transport (ESCRT) consists of several multi-protein subcomplexes which assemble sequentially at the endosomal surface and function in multivesicular body (MVB) biogenesis.
Lynn eRichardson, Alex eHoward, Nicholas eKhuu, Satinder eGidda, Andrew eMcCartney, Brett eMorphy, Robert eMullen   +6 more
doaj   +1 more source

ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting. [PDF]

, 2012
The sorting of signaling receptors to lysosomes is an essential regulatory process in mammalian cells. During degradation, receptors are modified with ubiquitin and sorted by endosomal sorting complex required for transport (ESCRT)-0, -I, -II, and -III ...
Chen, Buxin, Dores, Michael R, Lin, Huilan, Meerloo, Timo, Montagne, William A, Paing, May M, Soh, Unice JK, Trejo, JoAnn   +7 more
core   +3 more sources

ESCRT Machinery Mediates Cytokinetic Abscission in the Unicellular Red Alga Cyanidioschyzon merolae

Frontiers in Cell and Developmental Biology, 2020
In many eukaryotes, cytokinesis proceeds in two successive steps: first, ingression of the cleavage furrow and second, abscission of the intercellular bridge.
Fumi Yagisawa, Fumi Yagisawa, Takayuki Fujiwara, Takayuki Fujiwara, Takayuki Fujiwara, Tokiaki Takemura, Tokiaki Takemura, Yuki Kobayashi, Nobuko Sumiya, Shin-ya Miyagishima, Shin-ya Miyagishima, Shin-ya Miyagishima, Soichi Nakamura, Yuuta Imoto, Osami Misumi, Osami Misumi, Kan Tanaka, Haruko Kuroiwa, Tsuneyoshi Kuroiwa   +18 more
doaj   +1 more source

Inhibition of PIKFYVE kinase interferes ESCRT pathway to suppress RNA virus replication

Journal of Medical Virology, 2023
Endosomal sorting complex required for transport (ESCRT) is essential in the functional operation of endosomal transport in envelopment and budding of enveloped RNA viruses. However, in nonenveloped RNA viruses such as enteroviruses of the Picornaviridae
Zhen Luo, Yicong Liang, Mingfu Tian, Zhihui Ruan, Rui Su, M. Shereen, Jialing Yin, Kailang Wu, Jun Guo, Qiwei Zhang, Yongkui Li, Jianguo Wu   +11 more
semanticscholar   +1 more source

A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum

eLife, 2023
Cells are perpetually challenged by pathogens, protein aggregates or chemicals, that induce plasma membrane or endolysosomal compartments damage. This severe stress is recognised and controlled by the endosomal sorting complex required for transport ...
Lyudmil Raykov, Manon Mottet, J. Nitschke, Thierry Soldati   +3 more
semanticscholar   +1 more source

Exosomes and their dual role under viral infection

Zhongguo shuxue zazhi
Exosomes are extracellular vesicles that are released from the cell into the extracellular microenvironment, and are a carrier of biological information transmitted over long distances, which have a dual regulatory effect on the immune system.
Qianqian WEI, Limin CHEN, Yujia LI, Shilin LI   +3 more
doaj   +1 more source

Asgard archaea reveal the conserved principles of ESCRT-III membrane remodeling

Science Advances
ESCRT-III proteins assemble into composite polymers that undergo stepwise changes in composition and structure to deform membranes across the tree of life.
Diorge P. Souza, Javier Espadas, Sami Chaaban, E. R. Moody, Tomoyuki Hatano, Mohan K. Balasubramanian, Tom A. Williams, Aurélien Roux, B. Baum   +8 more
semanticscholar   +1 more source