Tyrosinase Inhibitor Activity of Coumarin-Resveratrol Hybrids [PDF]
, 2009 In the present work we report on the contribution of the coumarin moiety to tyrosinase inhibition. Coumarin-resveratrol hybrids 1-8 have been resynthesized to investigate the structure-activity relationships and the IC50 values of these compounds were
CORDA M +9 more
core +1 more source
Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo
Molecules, 2019 Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang +9 more
doaj +1 more source
Inhibition of Quorum Sensing and Biofilm Formation of Esculetin on Aeromonas Hydrophila
Frontiers in Microbiology, 2021 Quorum sensing (QS) and biofilm formation inhibition activity of esculetin on Aeromonas hydrophila SHAe 115 were evaluated. Exposure to esculetin at 25, 50, and 100μg/ml significantly inhibited the production of protease and hemolysin, the formation of ...
Bing Sun +5 more
doaj +1 more source
Secondary metabolites of alchemilla persica growing in Iran (East Azarbaijan) [PDF]
, 2015 Phytochemical investigations of Alchemilla persica Rothm. growing in Iran were performed taking into account both the volatile and polar constituents. The hydrodistilled essential oil was analysed by GC-MS that revealed the presence of diterpenoids (19.6
Afshar, Fariba Heshmati +4 more
core +1 more source
New properties of a bioinspired pyridine benzimidazole compound as a novel differential staining agent for endoplasmic reticulum and Golgi apparatus in fluorescence live cell imaging [PDF]
, 2018 Indexación: Scopus.In this study, we explored new properties of the bioinspired pyridine benzimidazole compound B2 (2,4-di-tert-butyl-6-(3H-imidazo[4,5-c]pyridine-2-yl)phenol) regarding its potential use as a differential biomarker.
Alexander Carreño +10 more
core +12 more sources
Umbelliferone and Esculetin: Inhibitors or Substrates for Polyphenol Oxidases?
Biological and Pharmaceutical Bulletin, 2008 Recently, an interesting debate arose about the nature (substrate versus inhibitor) of esculetin, a coumarin derivative, for mushroom polyphenol oxidase (PPO). The present study examined the behavior of PPOs preparations from fungal and plant origin towards esculetin as a substrate. Both enzymes were able to oxidize esculetin though at a slow rate.
Sollai, F +4 more
openaire +3 more sources
Biocontrol Ability and Action Mechanism of Starmerella bacillaris (Synonym Candida zemplinina) Isolated from Wine Musts against Gray Mold Disease Agent Botrytis cinerea on Grape and Their Effects on Alcoholic Fermentation [PDF]
, 2016 Gray mold is one of the most important diseases of grapevine in temperate climates. This plant pathogen affects plant growth and reduces wine quality. The use of yeasts as biocontrol agents to apply in the vineyard have been investigated in recent years ...
Bovo, Barbara +7 more
core +2 more sources
Mechanism and Effect of Esculetin in an Experimental Animal Model of Inflammatory Bowel Disease
European Journal of Inflammation, 2013 Esculetin is a coumarin derivative with high antioxidant activity. In a rat experimental model of inflammatory bowel disease induced by trinitrobenzenesulfonic acid, esculetin at the dose of 5mg/Kg displayed intestinal anti-inflammatory activity; however,
A. Witaicenis +8 more
doaj +1 more source
Challenges in the Heterologous Production of Furanocoumarins in Escherichia coli
Molecules, 2022 Coumarins and furanocoumarins are plant secondary metabolites with known biological activities. As they are present in low amounts in plants, their heterologous production emerged as a more sustainable and efficient approach to plant extraction. Although
Joana L. Rodrigues +2 more
doaj +1 more source
Candida albicans Modulates Host Defense by Biosynthesizing the Pro-Resolving Mediator Resolvin E1 [PDF]
, 2011 Candida albicans is an opportunistic fungal pathogen of humans that resides commensally on epithelial surfaces, but can cause inflammation when pathogenic. Resolvins are a class of anti-inflammatory lipids derived from omega-3 polyunsaturated fatty acids
Agabian, Nina +7 more
core +1 more source