Results 51 to 60 of about 4,540 (215)

An overview of genus Aesculus L.: ethnobotany, phytochemistry, and pharmacological Activities [PDF]

open access: yes, 2010
The genus Aesculus L. (Hippocastanaceae) has 12 species distributed in eastern Asia, eastern and western North America, and Europe. In Europe and the United States, A.
Li, Shiyou   +2 more
core   +2 more sources

Effect of esculetin on bone metabolism in ovariectomized rats

open access: yesJournal of Traditional Chinese Medicine, 2018
To determine the effect of an esculetin formulation (at 97.4% purity) on osteoporosis, and to investigate the potential underlying molecular mechanism(s).Sixty specific pathogen free-grade female Wistar rats were randomly assigned to three groups: blank control (n = 12), sham (n = 12), and model (n = 36). The model group were bilaterally ovariectomized.
Meijie, Liu   +11 more
openaire   +2 more sources

Protective Effects and Mechanisms of Esculetin against H2O2-Induced Oxidative Stress, Apoptosis, and Pyroptosis in Human Hepatoma HepG2 Cells

open access: yesMolecules
Oxidative stress plays a crucial role in the pathogenesis of many diseases. Esculetin is a natural coumarin compound with good antioxidant and anti-inflammatory properties.
Ying Luo   +5 more
doaj   +1 more source

Esculetin Alleviates Inflammation, Oxidative Stress and Apoptosis in Intestinal Ischemia/Reperfusion Injury via Targeting SIRT3/AMPK/mTOR Signaling and Regulating Autophagy

open access: yesJournal of Inflammation Research, 2023
Xin Shen,1,* Hai Shi,1,* Xinli Chen,1 Junwei Han,1 Haiwang Liu,1 Jie Yang,1 Yuan Shi,2 Jiajia Ma2 1Department of Gastrointestinal Surgery, Xi’an Daxing Hospital, Xi’an, 710016, People’s Republic of China; 2Department of Gynecology and Obstetrics,
Shen X   +7 more
doaj  

(E)-6-Hydroxy-2-oxo-2H-chromen-7-yl 3-(4-hydroxy-3-methoxyphenyl)acrylate

open access: yesMolbank, 2023
A hybrid compound 5: (E)-6-hydroxy-2-oxo-2H-chromen-7-yl 3-(4-hydroxy-3-methoxyphenyl)acrylate composed of (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (ferulic acid) 1 and 6,7-hydroxycoumarin (esculetin) 3 was prepared in a 61% yield by the ...
Yang-Heon Song
doaj   +1 more source

Diabetic Cardiovascular Disease Induced by Oxidative Stress. [PDF]

open access: yes, 2015
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure
Adam, Matti   +9 more
core   +2 more sources

Detection of coumarin derivatives of Viola odorata cultivated in Iraq

open access: yesJournal of Pharmacy and Bioallied Sciences, 2023
Like other members of the viola family, Viola odorata may be found naturally occurring in Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet.
Zainab Aziz Ali   +2 more
doaj   +1 more source

Characterization of thermophilic β-Glucosidase of rhizospheric bacterial strain (LSKB15) isolated from Cholistan Desert, Pakistan [PDF]

open access: yes, 2018
Fifty thermophilic bacterial strains isolated from rhizospheric soil of Cholistan desert, Pakistan, and designated as LSKB01-LSKB50 were screened for β-glucosidase gene (bgl) belonging to glycoside hydrolase family 1 (GH 1) using PCR technique ...
Ahmed, Amer   +4 more
core  

Candida albicans Modulates Host Defense by Biosynthesizing the Pro-Resolving Mediator Resolvin E1 [PDF]

open access: yes, 2011
Candida albicans is an opportunistic fungal pathogen of humans that resides commensally on epithelial surfaces, but can cause inflammation when pathogenic. Resolvins are a class of anti-inflammatory lipids derived from omega-3 polyunsaturated fatty acids
Agabian, Nina   +7 more
core   +1 more source

Deciphering the Chemotherapeutic Mechanism of Ferulic Acid: Insight Into the Role Against Multiple Human Cancers

open access: yesCancer Innovation, Volume 5, Issue 2, April 2026.
Ferulic acid (FA), a naturally occurring compound, exhibits anticancer activity against 16 cancer types through multiple molecular pathways. Its enhanced delivery via nanoformulations and synergistic effects with other therapies suggest FA as a promising, food‐based adjunct for cancer symptom control until fully approved pharmaceutical options are ...
Sanzida Khatun   +13 more
wiley   +1 more source

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