Results 51 to 60 of about 2,995 (191)
Study of Umbelliferone Hydroxylation to Esculetin Catalyzed by Polyphenol Oxidase
Biological and Pharmaceutical Bulletin, 2013 We characterize umbelliferone, a derivative of 2,4-dihydroxycoumaric acid, as a substrate of polyphenol oxidase. This enzyme hydroxylates umbelliferone to esculetin, its o-diphenol, and then oxidizes it to o-quinone. The findings show that umbelliferone, an intermediate in one of the coumarin biosynthesis pathways, may be transformed into its o ...
Garcia-Molina, Mary of the Sea +4 more
openaire +3 more sources
Cancer Innovation, Volume 5, Issue 2, April 2026.Ferulic acid (FA), a naturally occurring compound, exhibits anticancer activity against 16 cancer types through multiple molecular pathways. Its enhanced delivery via nanoformulations and synergistic effects with other therapies suggest FA as a promising, food‐based adjunct for cancer symptom control until fully approved pharmaceutical options are ...
Sanzida Khatun +13 more
wiley +1 more source
(E)-6-Hydroxy-2-oxo-2H-chromen-7-yl 3-(4-hydroxy-3-methoxyphenyl)acrylate
Molbank, 2023 A hybrid compound 5: (E)-6-hydroxy-2-oxo-2H-chromen-7-yl 3-(4-hydroxy-3-methoxyphenyl)acrylate composed of (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (ferulic acid) 1 and 6,7-hydroxycoumarin (esculetin) 3 was prepared in a 61% yield by the ...
Yang-Heon Song
doaj +1 more source
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Food Safety and Health, Volume 4, Issue 2, Page 327-342, April 2026.Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
Detection of coumarin derivatives of Viola odorata cultivated in Iraq
Journal of Pharmacy and Bioallied Sciences, 2023 Like other members of the viola family, Viola odorata may be found naturally occurring in Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet.
Zainab Aziz Ali +2 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 4, April 2026.Created in BioRender. Haralambie, O. (2025) https://BioRender.com/dh5ly89. ABSTRACT Digestive disorders such as inflammatory bowel disease (IBD) and colorectal cancer are among the most significant global health challenges, largely driven by chronic inflammation and oxidative stress.
Oana‐Roxana Haralambie, Sanda Andrei
wiley +1 more source
, 2016 Esculetin (6,7-dihydroxycoumarin) is a coumarin derivative extracted from natural plants and has been reported to have anti-cancer activity. However, the mechanism by which esculetin prevents human hepatic cancer cell growth is still largely unknown.
Li, Shuang +3 more
core +1 more source
ChemistryOpen, Volume 15, Issue 4, April 2026.Bioactive mesoporous silica nanoparticles (MSNPs) loaded with O. armenum extract were developed to evaluate their antibiofilm activity against biofilm‐forming Staphylococcus aureus ATCC 25923. The phytochemical content of the extract was analyzed via liquid chromatography–electrospray ionization tandem mass spectrometry.
Sevim Feyza Erdoğmuş +3 more
wiley +1 more source
Study of Esculetin-Induced Apoptosis in Human Gastric Carcinoma SGC-7901 Cells
, 2011 In order to investigate the effect and its mechanism of esculetin on human gastric carcinoma SGC-7901 cells, the effect of esculetin on human gastric carcinoma SGC-7901 cells were investigated by MTT method in vitro studies.
Yu Bin Ji, Shao Hua Jia
core +1 more source
, 2020 Hyperuricemia (HUA) is a risk factor for chronic kidney disease (CKD). Serum uric acid (SUA) levels in CKD stage 3–4 patients closely correlate with hyperuricemic nephropathy (HN) morbidity.
Tianyu Zhang +8 more
core +1 more source