Results 41 to 50 of about 4,540 (215)

Scopoletin 8-Hydroxylase-Mediated Fraxetin Production is Crucial for Iron Mobilization [PDF]

, 2018
Iron (Fe) is an essential mineral nutrient and an important factor for the composition of natural plant communities. Low Fe availability in aerated soils with neutral or alkaline pH has led to the evolution of elaborate mechanisms that extract Fe from ...
Lan, Ping, Rodríguez-Celma, Jorge, Schmidt, Wolfgang, Tsai, Huei-Hsuan, Vélez-Bermúdez, Isabel Cristina, Wu, Yu-Ching   +5 more
core   +1 more source

Biocontrol Ability and Action Mechanism of Starmerella bacillaris (Synonym Candida zemplinina) Isolated from Wine Musts against Gray Mold Disease Agent Botrytis cinerea on Grape and Their Effects on Alcoholic Fermentation [PDF]

, 2016
Gray mold is one of the most important diseases of grapevine in temperate climates. This plant pathogen affects plant growth and reduces wine quality. The use of yeasts as biocontrol agents to apply in the vineyard have been investigated in recent years ...
Bovo, Barbara, Carlot, Milena, Corich, Viviana, Crosato, Giulia, Favaron, Francesco, Giacomini, Alessio, Lemos, Wilson J, Nadai, Chiara   +7 more
core   +2 more sources

Umbelliferone and Esculetin: Inhibitors or Substrates for Polyphenol Oxidases?

Biological and Pharmaceutical Bulletin, 2008
Recently, an interesting debate arose about the nature (substrate versus inhibitor) of esculetin, a coumarin derivative, for mushroom polyphenol oxidase (PPO). The present study examined the behavior of PPOs preparations from fungal and plant origin towards esculetin as a substrate. Both enzymes were able to oxidize esculetin though at a slow rate.
Sollai, F, ZUCCA, PAOLO, SANJUST, ENRICO, STERI, DANIELA, RESCIGNO, ANTONIO   +4 more
openaire   +3 more sources

Mechanism and Effect of Esculetin in an Experimental Animal Model of Inflammatory Bowel Disease

European Journal of Inflammation, 2013
Esculetin is a coumarin derivative with high antioxidant activity. In a rat experimental model of inflammatory bowel disease induced by trinitrobenzenesulfonic acid, esculetin at the dose of 5mg/Kg displayed intestinal anti-inflammatory activity; however,
A. Witaicenis, A.C. Luchini, C.A. Hiruma-Lima, S.L. Felisbino, L.A. Justulin, N. Garrido-Mesa, P. Utrilla, J. Gálvez, L.C. Di Stasi   +8 more
doaj   +1 more source

Natural Coumarin Derivative Esculetin Regulates Platelet Activation via Modulating NF-κB Signaling in Cyclic Nucleotide-Independent Manner

Natural Product Communications, 2019
Esculetin, a natural coumarin derivative, shows exciting biological activities in a variety of cell and animal models. Our recent study demonstrated that esculetin exhibits antiplatelet effects by obstructing the phospholipase C γ2/protein kinase C ...
Chih-Wei Hsia, Kou-Gi Shyu, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Marappan Velusamy, Chih-Hao Yang, Joen-Rong Sheu   +6 more
doaj   +1 more source

Esculetin Provides Neuroprotection against Mutant Huntingtin-Induced Toxicity in Huntington’s Disease Models

Pharmaceuticals, 2021
Huntington’s disease (HD) is a neurodegenerative disorder caused by an abnormal CAG trinucleotide repeat expansion within exon 1 of the huntingtin (HTT) gene.
Letizia Pruccoli, Carlo Breda, Gabriella Teti, Mirella Falconi, Flaviano Giorgini, Andrea Tarozzi   +5 more
doaj   +1 more source

Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease [PDF]

, 2015
BackgroundInflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress might be involved in driving the oxidative stress–induced pathology.ObjectiveWe sought to ...
Vestbo, Chung, Mailloux, Rahman, Trachootham, Camougrand, Mills, Frezza, Archer, Osiewacz, Chung, Ichimaru, Eiswerth, Hollingsworth, Peng, Williams, Triantaphyllopoulos, Pryor, Enesa, Li, Wiegman, Chang, Michaeloudes, Williams, Perry, Smith, Hirota, Sohal, Li, Leo, Agarwal, Hoffmann, Kutsuzawa, Wuyam, Trian, Michaeloudes, Mabalirajan, Mabalirajan, Mabalirajan, Ito, Koshiba, Ricciardolo, Sugiura, Taylor, Aravamudan, Aravamudan, Hara   +46 more
core   +1 more source

Spectrophotometric Studies of Ferric-esculetin Complex

, 1963
Esculatin (6,7-dihydroxycoumarin) hes boon found to form soluble, coloured complexes at different pH with ferric ions. At pH 9.5 end 394m\(\mu\), the complex in 25% methanolic solution obeys Beer's law up to 1.8 p.p.m. of iron (III). Job's method of continued variation and electrophoretio studies have been used to sug­gest a tentative structure.
B. D. Jain, H. B. Singh
openaire   +1 more source

6,7-Dihydroxy-5,8-dimethoxy-2H-chromen-2-one

Molbank, 2023
This article presents a novel approach for synthesizing a new 5,8-dimethoxy derivative of esculetin via the selective cleavage of the methylene bridge in sabandin—naturally occurring and easily synthetically accessible methoxylated coumarin.
Olga I. Adaeva, Dmitry V. Demchuk, Victor V. Semenov   +2 more
doaj   +1 more source

Composition variation in essential oils of Artemisia nilagirica and Artemisia capillaris, growing in India [PDF]

, 2010
The present study was aimed to find out the chemical constituents of essential oils of Artemisia nilagirica (Clarke) Pamp. and Artemisia capillaris Thunb. of Asteraceae family, growing in Garhwal region of India. The essential oils were obtained by hydro-
Badoni, Ruchi, Rawat, Usha, Semwal, Deepak Kumar   +2 more
core   +2 more sources