Results 21 to 30 of about 2,492 (169)
Esculetin Alleviates Acute Liver Failure following Lipopolysaccharide/D-Galactosamine in Male C57BL/6 Mice [PDF]
Iranian Journal of Medical Sciences, 2021 Background: Acute liver failure (ALF) is a fatal clinical situation that rapidly leads to the loss of normal liver function. Esculetin is a natural herbal compound used for the management of various diseases such as cardiovascular and renal disorders. In
Seyed-Mahdi Mohamadi-Zarch +5 more
doaj +1 more source
Improvement effects of esculetin on the formation and development of atherosclerosis
Biomedicine & Pharmacotherapy, 2022 Atherosclerosis is one of the potential causes of death in patients with cardiovascular disease. With the discovery of new anti atherosclerotic drugs becoming the pursuit of the pharmaceutical industry, natural products have attracted more and more attention because of their unique efficacy in the treatment of atherosclerosis.
Qian-Hui, Wang +2 more
openaire +2 more sources
Molecules, 2022 Inflammation is a major root of several diseases such as allergy, cancer, Alzheimer’s, and several others, and the present state of existing drugs provoked researchers to search for new treatment strategies.
Thanasekaran Jayakumar +8 more
doaj +1 more source
Esculetin Ameliorates Psoriasis-Like Skin Disease in Mice by Inducing CD4+Foxp3+ Regulatory T Cells
Frontiers in Immunology, 2018 Psoriasis is an autoimmune and inflammatory skin disease affecting around 2–3% of the world's population. Patients with psoriasis need extensive treatments with global immunosuppressive agents that may cause severe side effects.
Yuchao Chen +7 more
doaj +1 more source
Toxics, 2022 We examined the protective effects of esculetin and fucoidan against the neurotoxicity of ZnO NPs in rats. Ninety rats were divided into nine groups and pre-treated with esculetin or fucoidan 1 h before ZnO NP administration on a daily basis for 2 weeks.
Woo-Ju Song +6 more
doaj +1 more source
The Arabidopsis NPF7.2 mediates coumarin uptake for root iron acquisition. [PDF]
New PhytolSummary Iron (Fe) is a transition metal necessary for achieving essential physiological processes throughout the plant lifecycle. In Arabidopsis thaliana, secreting Fe‐mobilizing coumarins (FMC) is a key mechanism enabling roots to acquire nonbioavailable Fe present in soils.
Watanabe S +7 more
europepmc +2 more sources
Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo
Molecules, 2019 Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang +9 more
doaj +1 more source
BMC Cancer, 2023 Background The “Differentiation therapy” has been emerging as a promising and more effective strategy against acute leukemia relapses. Objective In extension to the revolutionising therapeutic outcomes of All Trans Retinoic Acid (ATRA) to induce terminal
Ankit Mathur, Aman Gangwar, Daman Saluja
doaj +1 more source
Esculetin Inhibits Cancer Cell Glycolysis by Binding Tumor PGK2, GPD2, and GPI
Frontiers in Pharmacology, 2020 Glycolysis can improve the tolerance of tissue cells to hypoxia, and its intermediates provide raw materials for the synthesis and metabolism of the tumor cells.
Song-Tao Wu +16 more
doaj +1 more source
Inhibitory Effects of Esculetin on Melanin Biosynthesis
Biological and Pharmaceutical Bulletin, 2004 To investigate the structure-activity relationship of coumarins for the inhibitory activity on mushroom tyrosinase, the 50% inhibitory concentration (IC50 values) of 18 coumarins and four cinnamic acid derivatives were measured. Among these compounds, esculetin had the strongest inhibitory activity (IC50=43 microM) on mushroom tyrosinase.
Masamoto, Yukimitsu +5 more
openaire +3 more sources