Results 31 to 40 of about 4,540 (215)
Inhibitory Effects of Esculetin on Melanin Biosynthesis
Biological and Pharmaceutical Bulletin, 2004 To investigate the structure-activity relationship of coumarins for the inhibitory activity on mushroom tyrosinase, the 50% inhibitory concentration (IC50 values) of 18 coumarins and four cinnamic acid derivatives were measured. Among these compounds, esculetin had the strongest inhibitory activity (IC50=43 microM) on mushroom tyrosinase.
Yukimitsu, Masamoto +5 more
openaire +3 more sources
Veterinary Sciences, 2023 Mammary gland tumors are the most common neoplasms in female dogs, of which 50% are malignant. Esculetin, a coumarin derivative, reportedly induces death in different types of cancer cells.
Jawun Choi +3 more
doaj +1 more source
Metabolome analysis of Arabidopsis thaliana roots identifies a key metabolic pathway for iron acquisition [PDF]
, 2014 Fe deficiency compromises both human health and plant productivity. Thus, it is important to understand plant Fe acquisition strategies for the development of crop plants which are more Fe-efficient under Fe-limited conditions, such as alkaline soils ...
Böttcher, Christoph +7 more
core +3 more sources
Secondary metabolites of alchemilla persica growing in Iran (East Azarbaijan) [PDF]
, 2015 Phytochemical investigations of Alchemilla persica Rothm. growing in Iran were performed taking into account both the volatile and polar constituents. The hydrodistilled essential oil was analysed by GC-MS that revealed the presence of diterpenoids (19.6
Afshar, Fariba Heshmati +4 more
core +1 more source
Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo
Molecules, 2019 Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang +9 more
doaj +1 more source
BMC Pharmacology and Toxicology, 2021 Background Esculetin is a natural coumarin derivative from various plants with multiple pharmacological effects. Hence, the present study was undertaken to explore the cardio protective potential of esculetin against isoproterenol induced myocardial ...
Chitikela P. Pullaiah +4 more
doaj +1 more source
Tyrosinase Inhibitor Activity of Coumarin-Resveratrol Hybrids [PDF]
, 2009 In the present work we report on the contribution of the coumarin moiety to tyrosinase inhibition. Coumarin-resveratrol hybrids 1-8 have been resynthesized to investigate the structure-activity relationships and the IC50 values of these compounds were
CORDA M +9 more
core +1 more source
Esculetin Inhibits Cancer Cell Glycolysis by Binding Tumor PGK2, GPD2, and GPI
Frontiers in Pharmacology, 2020 Glycolysis can improve the tolerance of tissue cells to hypoxia, and its intermediates provide raw materials for the synthesis and metabolism of the tumor cells.
Song-Tao Wu +16 more
doaj +1 more source
New properties of a bioinspired pyridine benzimidazole compound as a novel differential staining agent for endoplasmic reticulum and Golgi apparatus in fluorescence live cell imaging [PDF]
, 2018 Indexación: Scopus.In this study, we explored new properties of the bioinspired pyridine benzimidazole compound B2 (2,4-di-tert-butyl-6-(3H-imidazo[4,5-c]pyridine-2-yl)phenol) regarding its potential use as a differential biomarker.
Alexander Carreño +10 more
core +12 more sources
Inhibition of Quorum Sensing and Biofilm Formation of Esculetin on Aeromonas Hydrophila
Frontiers in Microbiology, 2021 Quorum sensing (QS) and biofilm formation inhibition activity of esculetin on Aeromonas hydrophila SHAe 115 were evaluated. Exposure to esculetin at 25, 50, and 100μg/ml significantly inhibited the production of protease and hemolysin, the formation of ...
Bing Sun +5 more
doaj +1 more source