Results 51 to 60 of about 4,462 (212)
Pharmaceuticals, 2021 Huntington’s disease (HD) is a neurodegenerative disorder caused by an abnormal CAG trinucleotide repeat expansion within exon 1 of the huntingtin (HTT) gene.
Letizia Pruccoli +5 more
doaj +1 more source
2-Styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study [PDF]
, 2002 The purpose of this study was the evaluation of the xanthine oxidase (XO) inhibition produced by some synthetic 2-styrylchromones. Ten polyhydroxylated derivatives with several substitution patterns were synthesised, and these and a positive control,
Bastos, Maria de Lourdes +6 more
core +1 more source
Spectrophotometric Studies of Ferric-esculetin Complex
, 1963 Esculatin (6,7-dihydroxycoumarin) hes boon found to form soluble, coloured complexes at different pH with ferric ions. At pH 9.5 end 394m\(\mu\), the complex in 25% methanolic solution obeys Beer's law up to 1.8 p.p.m. of iron (III). Job's method of continued variation and electrophoretio studies have been used to suggest a tentative structure.
B. D. Jain, H. B. Singh
openaire +1 more source
6,7-Dihydroxy-5,8-dimethoxy-2H-chromen-2-one
Molbank, 2023 This article presents a novel approach for synthesizing a new 5,8-dimethoxy derivative of esculetin via the selective cleavage of the methylene bridge in sabandin—naturally occurring and easily synthetically accessible methoxylated coumarin.
Olga I. Adaeva +2 more
doaj +1 more source
Journal of Inflammation Research, 2023 Xin Shen,1,* Hai Shi,1,* Xinli Chen,1 Junwei Han,1 Haiwang Liu,1 Jie Yang,1 Yuan Shi,2 Jiajia Ma2 1Department of Gastrointestinal Surgery, Xi’an Daxing Hospital, Xi’an, 710016, People’s Republic of China; 2Department of Gynecology and Obstetrics,
Shen X +7 more
doaj
Effect of esculetin on bone metabolism in ovariectomized rats
Journal of Traditional Chinese Medicine, 2018 To determine the effect of an esculetin formulation (at 97.4% purity) on osteoporosis, and to investigate the potential underlying molecular mechanism(s).Sixty specific pathogen free-grade female Wistar rats were randomly assigned to three groups: blank control (n = 12), sham (n = 12), and model (n = 36). The model group were bilaterally ovariectomized.
Meijie, Liu +11 more
openaire +2 more sources
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Food Safety and Health, EarlyView.Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
(E)-6-Hydroxy-2-oxo-2H-chromen-7-yl 3-(4-hydroxy-3-methoxyphenyl)acrylate
Molbank, 2023 A hybrid compound 5: (E)-6-hydroxy-2-oxo-2H-chromen-7-yl 3-(4-hydroxy-3-methoxyphenyl)acrylate composed of (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (ferulic acid) 1 and 6,7-hydroxycoumarin (esculetin) 3 was prepared in a 61% yield by the ...
Yang-Heon Song
doaj +1 more source
Characterization of thermophilic β-Glucosidase of rhizospheric bacterial strain (LSKB15) isolated from Cholistan Desert, Pakistan [PDF]
, 2018 Fifty thermophilic bacterial strains isolated from rhizospheric soil of Cholistan desert, Pakistan, and designated as LSKB01-LSKB50 were screened for β-glucosidase gene (bgl) belonging to glycoside hydrolase family 1 (GH 1) using PCR technique ...
Ahmed, Amer +4 more
core
Food Frontiers, Volume 7, Issue 2, March 2026.ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source