Results 81 to 90 of about 2,995 (191)
Esculetin (6,7-dihydroxycoumarin), is one of coumarin analogs isolated from various plant including Cichorium intybus, Artemisia scoparia and Fraxinus japonica Blume, has been found to exhibit broaden biological effects, such as analgesic, anti ...
梁思成 +4 more
core
Nicotiana tabacum is a cash crop that originated in America and was introduced to the world by Christopher Colombus. It is now cultivated in many countries with major producers including China, the USA, India, and Brazil. The plant was widely used by the indigenous people of America for different reasons (spiritual, hallucination, and medical).
Abir Chami +4 more
wiley +1 more source
Deciphering the role of 12/15-lipoxygenase in asthma: insights into mitochondrial dysfunction and therapeutic implications [PDF]
This review delves into the complex role of 12/15-lipoxygenase (12/15-LOX) in asthma pathogenesis, focusing on its contributions to mitochondrial dysfunction, oxidative stress, epithelial injury, and airway remodeling.
Mandya V. Greeshma +5 more
doaj +1 more source
Integrated network pharmacology, molecular docking, and dynamics simulations revealed the anti‐osteoarthritis mechanism of Ermiao San. Key bioactive compounds (e.g., quercetin) synergistically target core proteins (e.g., TNF and IL‐6), modulating critical pathways (e.g., TNF signaling) to inhibit inflammation and cartilage degradation, demonstrating a ...
Zhenyu Song +8 more
wiley +1 more source
Fluorescent Behavior of Esculetin
Esculetin is a member of coumarin family, more importantly, as well as one of the big three natural coumarins that have most academic publications. The adjacent -OHs on 6 and 7 positions gives esculetin intriguing hydrogen bonding mechanism, and the ...
Muyskens, Mark, Tu, Yukun
core
Esculetin, a bioactive 6,7-dihydroxy derivative of coumarin, possesses pharmacological activities against obesity, diabetes, renal failure, and cardiovascular disorders (CVDs). Platelet activation plays a major role in CVDs.
Marappan Velusamy +8 more
core +1 more source
A novel simple, sensitive and selective electrochemical sensor was successfully prepared for the determination of esculetin in Cortex Fraxini based on the carboxylic acid-functionalized single-walled carbon nanotubes-Nafion–Au nanosol nanocomposite ...
Yuanyuan Yao +8 more
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Atopic dermatitis (AD) is a common chronic inflammatory skin disorder afflicting from infancy to adults with itching, scratching, and lichenification.
T K Kwon +23 more
core +1 more source
Esculetin Suppresses Proliferation of Human Colon Cancer Cells by Directly Targeting beta-Catenin
The Wnt pathway is a promising therapeutic and preventive target in various human cancers. The transcriptional complex of beta-catenin-T-cell factor (Tcf), a key mediator of canonical Wnt signaling, has been implicated in human colon cancer development ...
Lee, Mee-Hyun +23 more
core +1 more source

