Results 71 to 80 of about 5,623,526 (302)

AMINO ACID AND FATTY ACID PROFILES IN LOCAL TIGRIS CATFISH (SILURUS TRIOSTEGUS) MEAT [PDF]

open access: yesAssiut Veterinary Medical Journal
This study aimed to determine the pattern, composition, and ratios of fatty and amino acids in the meat of the local Tigris catfish (Silurus triostegus) to estimate its nutritional value.
MAZIN AL-ZUBAIDY, SURA AL-TAK
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Essential Amino Acids for Muscle Protein Accretion

open access: yes, 2010
SUMMARY: THE STIMULATION OF MUSCLE PROTEIN SYNTHESIS IS RELIANT ON THE ADEQUATE AVAILABILITY OF AMINO ACID (AA) PRECURSORS. THE INCREASE IN CIRCULATING AA CONCENTRATIONS IN THE BLOOD SERVES AS A SIGNAL TO INITIATE SYNTHETIC PROCESSES.
Wolfe, RR   +7 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The catalytic subunit of the system L1 amino acid transporter (Slc7a5) facilitates nutrient signalling in mouse skeletal muscle [PDF]

open access: yes, 2014
The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and cell ...
Adel F M Ibrahim   +31 more
core   +1 more source

Amino acids fortification of low-protein diet for broilers under tropical climate: ideal essential amino acids profile

open access: yesItalian Journal of Animal Science, 2014
A three-week trial was conducted to determine the effect of lowering dietary protein level (DPL) with optimal amino acid (AA) profile on growth performance, blood metabolites, and relative weights of abdominal fat and internal organs in broiler chickens ...
Elmutaz Atta Awad   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Hydrolytic amino acids in the fermented tea dregs.

open access: yes, 2021
TAA, total amino acids; TEAA, total essential amino acids; TNEAA, total non-essential amino acids; TAAA, total aromatic amino acids; TBCAA, total branched-chain amino acids. Values with the same letters were not significantly different (P< 0.05).
Jiazhou Li (8409465)   +6 more
core   +1 more source

Essential Amino Acids—Essential in Arterial Thrombosis [PDF]

open access: yesCirculation, 2020
Zachary T, Hilt, Craig N, Morrell
openaire   +2 more sources

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