Results 51 to 60 of about 720,855 (261)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Amino acid release patterns of growing pig diets formulated with different dietary protein sources

open access: yesJournal of Applied Animal Research, 2019
This study elucidated the dynamics of AA release in low-protein growing pig diets formulated with different protein sources. Four protein sources including soybean meal (SM), corn gluten meal (CGM), fish meal (FM) and fermented soybean meal (FSM) were ...
Abedin Abdallah   +5 more
doaj   +1 more source

Serum Amino Acids in Association with Prevalent and Incident Type 2 Diabetes in A Chinese Population

open access: yesMetabolites, 2019
We aimed to simultaneously examine the associations of both essential and non-essential amino acids with both prevalent and incident type 2 diabetes in a Chinese population.
Yonghai Lu   +7 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Species Variations in the Proximate Composition, Amino Acid Profile, and Protein Quality of the Muscle Tissue of Grass Carp, Bighead Carp, Siberian Sturgeon, and Wels Catfish

open access: yesJournal of Food Quality, 2018
This study determined the proximate composition, energy value, amino acid profile, and protein quality of the muscle tissue of four food fish species. The fish analyzed contained 78.90–69.89% water, 18.25–15.69% protein, and 2.28–12.57% fat.
Renata Pyz-Łukasik   +1 more
doaj   +1 more source

Characteristics of Tuna Viscera (Thunnus sp.) Hydrolysate Protein Fermented by Bacillus licheniformis

open access: yesResearch Journal of Life Science, 2020
This study aims to analyze the nutritional composition of the degree of hydrolysis and amino acids in the internal organ waste of tuna and the protein hydrolyzate of tuna's internal organs after fermentation using the Bacillus licheniformis bacteria. The
Galih Nugroho   +2 more
doaj   +1 more source

Essential Amino Acids—Essential in Arterial Thrombosis [PDF]

open access: yesCirculation, 2020
Zachary T, Hilt, Craig N, Morrell
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

AMINO ACID AND FATTY ACID PROFILES IN LOCAL TIGRIS CATFISH (SILURUS TRIOSTEGUS) MEAT [PDF]

open access: yesAssiut Veterinary Medical Journal
This study aimed to determine the pattern, composition, and ratios of fatty and amino acids in the meat of the local Tigris catfish (Silurus triostegus) to estimate its nutritional value.
MAZIN AL-ZUBAIDY, SURA AL-TAK
doaj   +1 more source

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