Results 51 to 60 of about 595,772 (318)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The synthesis and characterization of some ortho-substituted phenoxyalkanoic acids and their derivatives [PDF]

Journal of the Serbian Chemical Society, 2006
The synthesis of 2-phenoxyalkanoic acids (ethanoic, propanoic, butanoic) was realized by the reaction of ortho-hydroxybenzamide respectively N-phenyl-o-hydroxybenzamide with α-halogenated acids in aqueous sodium hydroxide solution.
Lupea Xenia Alfa, Popescu Iuliana, Tarabasanu Corneliu, Ienascu Ioana, Badea Valentin   +4 more
doaj   +1 more source

The Alkylation of Acetoacetic Ester by Toluenesulphonic Esters.

, 1935
The Alkylation of Acetoacetic Ester by Toluenesulphonic Esters.
C. NARAYANAN NAIR, D. H. PEACOCK
openaire   +2 more sources

Ester-Carbene and Its Dimerization with Exclusive Cis-Selectivity on a Silver Surface

, 2022
Diazo compounds are key precursors to carbenes. Here, methyl diazoacetate is dosed onto an Ag(111) surface and subjected to 365 nm UV light activation.
Chao-Ming Chiang, Chi-Wi Ong, Chia-Hung Wu, Chi-Wi Ong (12029380), Jean-Ho Chu, Chih-Hung Chou (1777063), Po-Chiao Lin (1777066), Po-Chiao Lin, Chia-Hung Wu (1264359), Chih-Hung Chou, Jean-Ho Chu (1425892), Chao-Ming Chiang (1280214)   +11 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Suicide among agricultural, forestry, and fishery workers: a systematic literature review and meta-analysis

Scandinavian Journal of Work, Environment & Health, 2018
OBJECTIVES: This review aimed to quantify suicide risk among agricultural, forestry, and fishery workers and study potential variations of risk within this population.
Justine Klingelschmidt, Allison Milner, Imane Khireddine-Medouni, Katrina Witt, Evangelos C Alexopoulos, Susanna Toivanen, Anthony D LaMontagne, Jean-François Chastang, Isabelle Niedhammer   +8 more
doaj   +1 more source

Ester-Armed Cyclens Having Quadruplicated Helical Geometry:  Remarkably Stable and Selective Encapsulation of Na⁺ Ion

, 2016
A new series of ester-armed cyclens nicely accommodated a Na+ ion in their quadruplicated helical binding spheres and effectively discriminated the cation from Li+ and K+ ions.
Satoshi Shinoda (2185645), Makoto Tadokoro (2317819), Tomoko Nishimura (50428), Hiroshi Tsukube (1431313)   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Susceptibility of Escherichia coli and Clostridium perfringens to sucrose monoesters of capric and lauric acid

Czech Journal of Animal Science, 2014
The sucrose monoesters of capric and lauric acid were tested for their antibacterial activity towards two foodborne enteropathogenic bacteria - Escherichia coli (CCM 3954 - serotype O6 and E22 - serotype O103) and Clostridium perfringens (CNCTC 5459 and ...
E. Skřivanová, Š. Pražáková, O. Benada, P. Hovorková, M. Marounek   +4 more
doaj   +1 more source