A new method for the separation of androgens from estrogens and for the partition of estriol from the estrone-estradiol fraction: with special reference to the identification and quantitative microdetermination of estrogens by ultraviolet absorption spectrophotometry [PDF]
, 1948 It is recognized generally that a qualitative and quantitative knowledge of the excretion pattern of the urinary estrogens is one index to an understanding of the functional activity of the ovary and adrenal cortex.
Friedgood, Harry B. +2 more
core
The Zebrafish (Danio rerio) Is a Relevant Model for Studying Sex-Specific Effects of 17β-Estradiol in the Adult Heart [PDF]
, 2019 Cardiovascular diseases are a major cause of morbidity and mortality, and there are significant sex differences therein. However, the underlying mechanisms are poorly understood.
Hassel, David +2 more
core +1 more source
Oxidative Metabolism of Estradiol
Journal of Biological Chemistry, 1960 The metabolism of the estrogenic hormone is oxidative in nature in contrast to the reductive pathway for the neutral steroid hormones. It has been postulated that estrone is the precursor of estriol on the evidence that the required ketol intermediates are normal metabolites of the estrogenic hormone (2-4).
T. F. Gallagher +2 more
openaire +3 more sources
Sex Steroid-Mediated Control of Oviductal Function in Cattle
Biology, 2018 In cattle, the oviduct is a tubular organ that connects the ovary and the uterus. The oviduct lumen stages a dynamic set of cellular and molecular interactions to fulfill the noble role of generating a new individual. Specific anatomical niches along the
Mario Binelli +3 more
doaj +1 more source
Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. [PDF]
, 2020 Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones.
Biglia, Nicoletta +14 more
core +4 more sources
β-Estradiol and ethinyl-estradiol contamination in the rivers of the Carpathian Basin [PDF]
Environmental Science and Pollution Research, 2016 17β-Estradiol (E2) and 17α-ethinyl estradiol (EE2), which are environmental estrogens, have been determined with LC-MS in freshwater. Their sensitive analysis needs derivatization and therefore is very hard to achieve in multiresidue screening. We analyzed samples from all the large and some small rivers (River Danube, Drava, Mur, Sava, Tisza, and Zala)
Avar, Péter Ágoston +6 more
openaire +3 more sources
Elevated plasma ceramide levels in post-menopausal women: a cross-sectional study. [PDF]
, 2019 Circulating ceramide levels are abnormally elevated in age-dependent pathologies such as cardiovascular diseases, obesity and Alzheimer's disease.
Armirotti, Andrea +9 more
core +1 more source
Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]
, 2018 Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara +5 more
core +2 more sources
Inhibition of estradiol synthesis impairs fear extinction in male rats
Learning & memory (Cold Spring Harbor, N.Y.), 2014 Emerging research has demonstrated that the sex hormone estradiol regulates fear extinction in female rodents and women. Estradiol may also regulate fear extinction in males, given its role in synaptic plasticity in both sexes.
B. Graham, M. Milad
semanticscholar +1 more source
Neuroprotective actions of estradiol revisited [PDF]
Trends in Endocrinology & Metabolism, 2011 Results from animal experiments showing that estradiol is neuroprotective were challenged 10 years ago by findings indicating an increased risk of dementia and stroke in women over 65 years of age taking conjugated equine estrogens. Our understanding of the complex signaling of estradiol in neural cells has recently clarified the causes of this ...
Azcoitia Elías, Iñigo +3 more
openaire +6 more sources