Results 71 to 80 of about 173,634 (281)

Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae

Frontiers in Endocrinology, 2018
Teleost fish are known to express two isoforms of P450 aromatase, a key enzyme for estrogen synthesis. One of the isoforms, brain aromatase (AroB), cyp19a1b, is highly expressed during early development of zebrafish, thereby suggesting its role in brain ...
Zulvikar Syambani Ulhaq, Mitsuyo Kishida
doaj   +1 more source

Estradiol Regulation of Insulin-Like Growth Factor-I Expression in Osteoblastic Cells: Evidence for Transcriptional Control [PDF]

, 1991
Matthias Ernst, Gideon A. Rodan
openalex   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

Frontiers in Endocrinology
The aged population, expected to double by 2050, makes up a large proportion of people living with metabolic disease. Obesity rates in the elderly are rapidly increasing, with estimates that nearly 40% of men and women over the age of 60 are classified ...
Angel A. Lee, Angel A. Lee, Laura J. Den Hartigh, Laura J. Den Hartigh   +3 more
doaj   +1 more source

Sex Hormones Are Associated With Rumination and Interact With Emotion Regulation Strategy Choice to Predict Negative Affect in Women Following a Sad Mood Induction

Frontiers in Psychology, 2018
Women are particularly vulnerable to anxiety and depressive disorders. This greater vulnerability has been partly attributed to post-pubertal sex hormone fluctuations, estradiol and progesterone, as well as gender-specific tendencies to engage in ...
Bronwyn M. Graham, Thomas F. Denson, Justine Barnett, Clare Calderwood, Jessica R. Grisham   +4 more
doaj   +1 more source

Treatment of Endometriosis with the GnRHa Deslorelin and Add-Back Estradiol and Supplementary Testosterone [PDF]

, 2015
Sanjay K. Agarwal, AnnaMarie Daniels, S.R. Drosman, Laurence C. Udoff, Warren G. Foster, Malcolm C. Pike, Darcy Spicer, John R. Daniels   +7 more
openalex   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Steroid anabolic and catabolic hormones in highly and recreationally trained female athletes across the menstrual cycle

Physiological Reports
Sex hormone fluctuations across the normal menstrual cycle (NMC) may affect women's performance and health, but literature is sparse on the estradiol (E2) impact on anabolic and catabolic hormones and well‐being in female athletes.
Katia Collomp, Carole Castanier, Caroline Teulier, Agnès Olivier, Léane Blanchard, Juliette Bonnigal, Emmanuelle Duron, Eric Favory, Mathieu Zimmermann, Virgile Amiot, Valérie Carité, Marine Lefebvre, Cynthia Mongongu, Magnus Ericsson, Corinne Buisson   +14 more
doaj   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source