Results 71 to 80 of about 303,077 (183)

The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells [PDF]

, 2016
The angiogenic inducer CCN1 (Cysteine-rich 61, CYR61) is differentially activated in metastatic breast carcinomas. However, little is known about the precise mechanisms that underlie the pro-metastatic actions of CCN1. Here, we investigated the impact of
Espinoza, Ingrid, Lupu, Ruth, Menendez, Javier A., Vellón, Luciano   +3 more
core   +1 more source

Effects of Testosterone and Its Major Metabolites upon Different Stages of Neuron Survival in the Dentate Gyrus of Male Rats

Biomolecules
Testosterone has been shown to enhance hippocampal neurogenesis through increased cell survival, but which stages of new neuron development are influenced by testosterone remains unclear.
Mark D. Spritzer, Ethan A. Roy, Kelsey M. K. Calhoun, Zachary E. Schneider-Lynch, Leslie Panella, Charlotte Michaelcheck, April Qian, Evan D. Kelly, Hadley Barr, Emma Hall, Blaine Cunningham, Hieu H. M. Nguyen, Dani Xu, Jennifer M. Barker, Liisa A. M. Galea   +14 more
doaj   +1 more source

Decreased nitric oxide levels in the hippocampus may play a role in learning and memory deficits in ovariectomized rats treated by a high dose of estradiol

Arquivos de Neuro-Psiquiatria, 2012
The effects of a high estradiol dose on memory and on nitric oxide metabolites in hippocampal tissues were investigated. Sham-Est and OVX-Est Groups were treated with 4 mg/kg of estradiol valerate for 12 weeks.
Reihaneh Sadeghian, Masoud Fereidoni, Mohammad Soukhtanloo, Hamid Azizi-Malekabadi, Mahmoud Hosseini   +4 more
doaj   +1 more source

Removal of endocrine disrupting chemicals using low pressure reverse osmosis membrane [PDF]

, 2009
Endocrine disrupting chemicals (EDCs) are one of the major focuses of contaminants in current environmental issues, as they can cause adverse health effects on animals and human, particularly to endocrine function.
Abd. Razak, Azri Rasyidi
core  

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]

, 2019
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R., Chen, Neal X., Hill Gallant, Kathleen M., Lachcik, Pamela J., Metzger, Corinne E., Moe, Sharon M., Swallow, Elizabeth A., Vorland, Colby J.   +7 more
core   +1 more source

Serum interleukin-17 expression in postmenopausal women and its relation to osteoporosis and risk of fractures

Journal of the Arab Society for Medical Research
Background/Aim Osteoporosis is a musculoskeletal disorder that is characterized by low bone mineral density (BMD) as well as an elevated risk of fractures.
Samar G. Soliman, Samah S. Youssef, Amira K. Mohammed, Dalia S. Saif   +3 more
doaj   +1 more source

Tamoxifen: an FDA approved drug with neuroprotective effects for spinal cord injury recovery

Neural Regeneration Research, 2016
Spinal cord injury (SCI) is a condition without a cure, affecting sensory and/or motor functions. The physical trauma to the spinal cord initiates a cascade of molecular and cellular events that generates a non-permissive environment for cell survival ...
Jennifer M Colón, Jorge D Miranda
doaj   +1 more source

Weak if any effect of estrogen on spatial memory in rats [PDF]

, 2002
In a number of species, males appear to have spatial abilities that are superior to those of females. The favored explanation for this cognitive difference is hormonal: higher testosterone levels in males than in females.
Farkas, Tamás, Kis, Zsolt, Németh, Hajnalka, Toldi, József, Tóth, Tünde, Varga, Hedvig   +5 more
core  

The direct response of the gonads to cues of stress in a temperate songbird species is season-dependent. [PDF]

, 2013
The gonadotropin releasing hormone (GnRH) system in the hypothalamus is often considered the final point in integration of environmental cues as they pertain to the reproductive axis.
Bentley, George, Koh, Annie, McGuire, Nicolette   +2 more
core   +2 more sources

Tumor and peritumoral tissue hormonal background features in patients with rare types of endometrial cancer

Исследования и практика в медицине
Serous endometrial intraepithelial carcinoma (SEIC) and clear cell carcinoma of the endometrium (CCEC) belong to pathogenetic type II without evidence of hyperestrogenism, are often detected late in the course of the disease, and are characterized by an ...
E. M. Frantsiyants, V. A. Bandovkina, A. P. Menshenina, T. I. Moiseenko, M. A. Rogozin, Yu. A. Pogorelova, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, N. D. Cheryarina, E. V. Verenikina   +10 more
doaj   +1 more source