Results 131 to 140 of about 1,887 (154)

Basil essential oil: Estragole content and chemical profiles

Acta Alimentaria
AbstractBasil (sweet basil, Ocimum basilicum L.) is an aromatic plant known for its culinary and traditional medicinal uses.The content of estragole (methyl chavicol), a compound associated with a potential risk to human health, was determined in the essential oils of 12 samples of basil herb by gas chromatography with flame ionisation and mass ...
J. Arsenijević, A. Jovanović, N. Kovačević, M. Drobac   +3 more
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Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats

Archives of Toxicology, 2012
Estragole (ES) is a natural organic compound used frequently as a flavoring food additive. Although it has been reported to be tumorigenic and induce DNA adducts in the mouse liver, there have been no reports regarding ES hepatocarcinogenicity in rats. In the current study, we therefore examined potent carcinogenicity, DNA adduct formation and in vivo ...
Yuta, Suzuki, Takashi, Umemura, Daisuke, Hibi, Tomoki, Inoue, Meilan, Jin, Yuji, Ishii, Hiroki, Sakai, Takehiko, Nohmi, Tokuma, Yanai, Akiyoshi, Nishikawa, Kumiko, Ogawa   +10 more
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Comparative study of the anti-edematogenic effects of anethole and estragole

Pharmacological Reports, 2012
Anethole and estragole are monoterpene position isomers and constituents of essential oils from aromatic plants and were used in this study with the aim of analyzing their anti-inflammatory activity.The anti-edematogenic effects of anethole and estragole were evaluated through plethysmometry in Swiss mice.Anethole inhibited carrageenan-induced edema at
Edson L, Ponte, Paloma L, Sousa, Maria V A P, Rocha, Pedro M G, Soares, Andrelina N, Coelho-de-Souza, José H, Leal-Cardoso, Ana M S, Assreuy   +6 more
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Ruthenium-catalyzed estragole isomerization: high trans-selective formation of anethole

Green Chemistry, 2010
Complexes [RuCl2(η6-C6H5OCH2CH2OH)(L)] (L = P(OMe)3 (1a), P(OEt)3 (1b), P(OiPr)3 (1c), P(OPh)3 (1d), PPh3 (1e)) have shown to be efficient catalysts for the isomerization of estragole into anethole, the best activities being obtained in polar solvents (water, methanol, ethanol).
Beatriz Lastra-Barreira, Pascale Crochet
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Determination of estragole, safrole and eugenol methyl ether in food products

Food Chemistry, 2003
Abstract A rapid and effective procedure for the extraction and determination of 4-allylanisole (estragole), 4-allyl-1,3-benzodioxole (safrole) and 4-allyl-1,2-dimetoxybenzene (eugenol methyl ether) in food products was developed. These compounds were isolated from food matrices by employing a simultaneous distillation–extraction (SDE) technique with
SIANO F., GHIZZONI C., GIONFRIDDO F., COLOMBO E., SERVILLO, Luigi, CASTALDO D.   +5 more
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Estragole: A weak direct-acting food-borne genotoxin and potential carcinogen

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2012
We evaluated the genotoxicity of the food-flavouring agent estragole in V79 cells using the sister chromatid exchange (SCE) assay and the alkaline comet assay. Unexpectedly, we observed an increase in SCE without an exogenous biotransformation system (S9) and a decrease in its presence.
Martins, Célia, Cação, Raquel, Cole, Kathleen J, Phillips, David H, Laires, António, Rueff, José, Rodrigues, António S   +6 more
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Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes

Chemical Research in Toxicology, 2007
Human cytochrome P450 enzymes involved in the bioactivation of estragole to its proximate carcinogen 1'-hydroxyestragole were identified and compared to the enzymes of importance for 1'-hydroxylation of the related alkenylbenzenes methyleugenol and safrole. Incubations with Supersomes revealed that all enzymes tested, except P450 2C8, are intrinsically
Jeurissen, S.M.F., Punt, A., Boersma, M.G., Bogaards, J.J.P., Fiamegos, Y.C., Schilter, B., van Bladeren, P.J., Cnubben, N.H.P., Rietjens, I.M.C.M.   +8 more
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Safety assessment of allylalkoxybenzene derivatives used as flavouring substances — methyl eugenol and estragole

Food and Chemical Toxicology, 2002
This publication is the seventh in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers' Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavouring substances under conditions of intended use.
Smith, R.L., Adams, T.B., Doull, J., Feron, V.J., Goodman, J.I., Marnett, L.J., Portoghese, P.S., Waddell, W.J., Wagner, B.M., Rogers, A.E., Caldwell, J., Sipes, I.G.   +11 more
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Synthesis of Nitrogen-Containing Heterocycles from Estragole

Russian Journal of Organic Chemistry, 2022
A. A. Smolyak, Yu. V. Shklyaev
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Line or threshold? Evolving toxicological views on estragole

Zeitschrift für Phytotherapie, 2023
H Sievers, O Kelber
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