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Bioactivation of estragole and anethole leads to common adducts in DNA and hemoglobin [PDF]
Food and Chemical Toxicology, 2021 Estragole and anethole are secondary metabolites occurring in a variety of commonly used herbs like fennel, basil, and anise. Estragole is genotoxic and carcinogenic in rodents, which depends on the formation of 1'-sulfoxyestragole after hydroxylation and subsequent sulfoconjugation catalyzed by CYP and SULT, respectively.
Nick Bergau +2 more
exaly +4 more sources
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Constituents of aromatic plants: II. Estragole
Fìtoterapìâ, 2000Estragole (ES) is a natural constituent of a number of plants (e.g. tarragon, sweet basil and sweet fennel) and their essential oils have been widely used in foodstuffs as flavouring agents. Several studies with oral, i.p. or s.c. administration to CD-1 and B6C3F1 mice have shown the carcinogenicity of ES.
Marco Silano, Beatrice Scazzocchio
exaly +3 more sources
Conformational, structural and vibrational studies of estragole
Vibrational Spectroscopy, 2021Abstract Structural and conformational investigations were carried out at the B3LYP/6-311++G** level using the Gaussian 09 software. Vibrational spectra along with other related parameters like molecular geometries; APT charges etc were computed to analyze the experimentally measured Raman and IR spectra.
Rohit Kumar Yadav +4 more
openaire +1 more source
Comparative study of the anti-edematogenic effects of anethole and estragole
Pharmacological Reports, 2012Anethole and estragole are monoterpene position isomers and constituents of essential oils from aromatic plants and were used in this study with the aim of analyzing their anti-inflammatory activity.The anti-edematogenic effects of anethole and estragole were evaluated through plethysmometry in Swiss mice.Anethole inhibited carrageenan-induced edema at
Pedro Marcos Gomes Soares +2 more
exaly +3 more sources
Quantitation of estragole by stable isotope dilution assays
LWT - Food Science and Technology, 2009 Various calibration strategies for the quantitation of the phenylpropane estragole by gas chromatography-mass spectrometry were developed and compared. For application in stable isotope dilution assays, two deuterium labelled estragole isotopologues were synthesized.
Michael Rychlik
exaly +3 more sources
Carbohydrate Polymer Technologies and Applications, 2023 Background: The need of the growth the production of more efficient medications for the control of bacterial infections has waked up the pharmaceutical industry to develop new drugs from compounds isolated from plants. Purpose: Therefore, the aim of the present study is to investigate the antimicrobial potential of the essential oil of Ocimum basilicum
Jacqueline Cosmo Andrade-Pinheiro +2 more
exaly +3 more sources
Food and Chemical Toxicology, 2011
Quantification of estragole content in commercial fennel herbal teas was carried out in order to allow for a more accurate estimate of the dietary exposure to estragole. A simple and rapid analytical method, based on Stir Bar Sorptive Extraction and GC-MS, was developed for this purpose.
Antonio, Raffo +2 more
openaire +2 more sources
Quantification of estragole content in commercial fennel herbal teas was carried out in order to allow for a more accurate estimate of the dietary exposure to estragole. A simple and rapid analytical method, based on Stir Bar Sorptive Extraction and GC-MS, was developed for this purpose.
Antonio, Raffo +2 more
openaire +2 more sources
Chemie in unserer Zeit, 2018
ZusammenfassungEstragol ist ein in vielen Pflanzen aus L‐Phenylalanin gebildetes Phenylpropanoid. Es kommt auch im ätherischen Öl des Französischen Estragons vor, aus dem es destillativ abgetrennt wurde. Estragon zählt neben Schnittlauch, Petersilie und Kerbel zu den vier Fines Herbes der französischen Haute Cuisine.
Agneta Prasse +4 more
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ZusammenfassungEstragol ist ein in vielen Pflanzen aus L‐Phenylalanin gebildetes Phenylpropanoid. Es kommt auch im ätherischen Öl des Französischen Estragons vor, aus dem es destillativ abgetrennt wurde. Estragon zählt neben Schnittlauch, Petersilie und Kerbel zu den vier Fines Herbes der französischen Haute Cuisine.
Agneta Prasse +4 more
openaire +1 more source
Estragole‐induced behavioural changes in rats
Phytotherapy Research, 2004AbstractCroton zehntneri is a popular plant used in the Brazilian folk medicine. Recently, the use of its essential oil showed depressive activity on the central nervous system (CNS). Chemical studies show that estragole (ES) is one of the main compounds of this oil.
Rosana M, Cosentino +2 more
openaire +2 more sources