Results 51 to 60 of about 2,198,676 (277)

A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen [PDF]

, 2012
SynthSys is a Centre for Integrative Systems Biology (CISB) funded by BBSRC and EPSRC, reference BB/D019621/1.Background: Estrogen receptors alpha (ER) are implicated in many types of female cancers, and are the common target for anti-cancer therapy ...
Harrison, David J, Kenneth Macleod, Yamaguchi, Azusa, Macleod, Kenneth, Galina Lebedeva, David J Harrison, Lebedeva, Galina, Langdon, Simon P., Langdon, Simon P, Azusa Yamaguchi, Harrison, David J., Simon P Langdon   +11 more
core   +1 more source

Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]

, 2010
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Beatrice E. Bachmeier, Ulrich Pfeffer, Killian, Peter H., Blengio, Fabiola, Valentina Mirisola, Romeo, Francesco, Dell'Eva, Raffaella, Pfeffer, Ulrich, Luca Generoso, Fabiola Blengio, Alessia Esposito, Raffaella Dell’Eva, Mirisola, Valentina, Generoso, Luca, Albini, Adriana, Adriana Albini, Peter H. Killian, Bachmeier, Beatrice E., Esposito, Alessia, Francesco Romeo   +19 more
core   +1 more source

Cholesteryl ester transfer protein alters liver and plasma triglyceride metabolism through two liver networks in female mice[S]

Journal of Lipid Research, 2016
Elevated plasma TGs increase risk of cardiovascular disease in women. Estrogen treatment raises plasma TGs in women, but molecular mechanisms remain poorly understood.
Brian T. Palmisano, Thao D. Le, Lin Zhu, Yoon Kwang Lee, John M. Stafford   +4 more
doaj   +1 more source

Occurrence of lymphoma in non-gonadal organ during pregnancy: a report on four cases and literature review

Cancer Biology & Medicine, 2016
Lymphoma rarely occurs during pregnancy, making this condition difficult to define. Lymphomas that occur in reproductive organs during pregnancy exhibit unique clinical characteristics.
Da-Lin Gao, Qian-Qian Fu, Tian-Tian Zhang, Lin Sun, Yi Pan, Qiong-Li Zhai   +5 more
doaj   +1 more source

The Role of Estrogen Receptors in Urothelial Cancer

Frontiers in Endocrinology, 2021
Epidemiological data have indicated that there are some sex-related differences in bladder cancer. Indeed, the incidence of bladder cancer in men has been substantially higher than that in women throughout the world, while women tend to have higher stage
Takuro Goto, Takuro Goto, Hiroshi Miyamoto, Hiroshi Miyamoto, Hiroshi Miyamoto   +4 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Motif analysis of amphioxus, lamprey and invertebrate estrogen receptors and amphioxus and human estrogen-related receptors: Towards a better understanding of estrogen receptor evolution [PDF]

, 2008
*Background.* The origins of steroid-dependent regulation of the vertebrate estrogen receptor (ER) are poorly understood. Genes with statistically significant sequence similarity to vertebrate ERs have been found in lamprey, a basal vertebrate, and ...
Michael E. Baker, Charlie Chandsawangbhuwana   +1 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Additional file 1: of Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

, 2016
File S1 Primers used for RT-qPCR. (PDF 14 kb)
SchĂźler-Toprak, Susanne, HäRing, Julia, Inwald, Elisabeth, Moehle, Christoph, Ortmann, Olaf, Treeck, Oliver   +5 more
openaire   +1 more source

Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer [PDF]

, 2009
Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells.
Yusuke Nakamura, Tomomi Ueki, Miki Akiyama, Meng-Lay Lin, Arata Shimo, Jae-Hyun Park, Yataro Daigo, Toyomasa Katagiri, Tatsuhiko Tsunoda, Jung-Won Kim, Toshihiko Nishidate   +10 more
core