Results 51 to 60 of about 306,344 (322)

The Role of Estrogen Receptors in Urothelial Cancer

Frontiers in Endocrinology, 2021
Epidemiological data have indicated that there are some sex-related differences in bladder cancer. Indeed, the incidence of bladder cancer in men has been substantially higher than that in women throughout the world, while women tend to have higher stage
Takuro Goto, Takuro Goto, Hiroshi Miyamoto, Hiroshi Miyamoto, Hiroshi Miyamoto   +4 more
doaj   +1 more source

Additional file 1: of Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells

, 2019
Table S1 Primers used for RT-qPCR analyses. (DOCX 14 kb)
Treeck, Oliver, Diepolder, Elisabeth, Skrzypczak, Maciej, SchĂźler-Toprak, Susanne, Ortmann, Olaf   +4 more
openaire   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Additional file 1: of Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

, 2018
Antibodies used in this study. (DOCX 12 kb)
SchĂźler-Toprak, Susanne, Weber, Florian, Skrzypczak, Maciej, Ortmann, Olaf, Treeck, Oliver   +4 more
openaire   +1 more source

Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 [PDF]

, 2017
The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys.
Eugster, Erica A., Neyman, Anna
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

miR-190 enhances endocrine therapy sensitivity by regulating SOX9 expression in breast cancer

Journal of Experimental & Clinical Cancer Research, 2019
Background Breast cancer is the most common cancer among women worldwide, and approximately 70% of breast cancers are hormone receptor-positive and express estrogen receptor-α (ERα) or/and progesterone receptor.
Yue Yu, Wen Yin, Zhi-Hao Yu, Yan-Jun Zhou, Jiang-Rui Chi, Jie Ge, Xu-Chen Cao   +6 more
doaj   +1 more source

Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells

Cell Death Discovery, 2021
Breast cancer is the most common cancer with a high rate of mortality and morbidity among women worldwide. Estrogen receptor status is an important prognostic factor and endocrine therapy is the choice of first-line treatment in ER-positive breast cancer.
Bahriye Karakas, Yeliz Aka, Asli Giray, Sehime Gulsun Temel, Ufuk Acikbas, Huveyda Basaga, Ozgur Gul, Ozgur Kutuk   +7 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Estrogen receptor β agonist inhibits proliferation of endometrial stromal cells in an estrogen-receptor independent manner [PDF]

Archives of Biological Sciences, 2014
The finding that estrogen receptor ERβ agonists induce regression of ectopic endometrial implants in a rodent model has rekindled interest in the role of ERβ in the growth and maintenance of human endometriosis.
Xia Qiong, Zhao Dong, Wang Juan
doaj   +1 more source