Results 41 to 50 of about 106,810 (131)

Estrogen receptor α dependent regulation of estrogen related receptor β and its role in cell cycle in breast cancer

BMC Cancer, 2018
Background Breast cancer (BC) is highly heterogeneous with ~ 60–70% of estrogen receptor positive BC patient’s response to anti-hormone therapy. Estrogen receptors (ERs) play an important role in breast cancer progression and treatment.
B. Madhu Krishna, Sanjib Chaudhary, Dipti Ranjan Mishra, Sanoj K. Naik, S. Suklabaidya, A. K. Adhya, Sandip K. Mishra   +6 more
doaj   +1 more source

Heterogeneity of estrogen and β-adrenergic receptors in female human coronary artery endothelial cells

International Journal of Cardiology: Heart & Vasculature
Introduction: Estrogen protects vascular function, likely via adrenergic modulation. Previous studies of estrogen and beta-adrenoceptor (β-AR) interactions relied on non-coronary or animal models, limiting relevance to human coronary endothelium.
Basant Elsaid, Irakli Kopaliani, Ansam Seif, Stephan Speier, Andreas Deussen   +4 more
doaj   +1 more source

Zearalenone Promotes Uterine Development of Weaned Gilts by Interfering with Serum Hormones and Up-Regulating Expression of Estrogen and Progesterone Receptors

Toxins, 2022
In this study, we aimed to assess the effect of diet ZEA on serum hormones, the location and expression of estrogen receptor ERα/β and progesterone receptor (PR) of the uterus in weaned piglets and to reveal the mechanism underneath.
Tingting Song, Xuemei Zhou, Xiangming Ma, Yanping Jiang, Weiren Yang, Faxiao Liu, Mei Liu, Libo Huang, Shuzhen Jiang   +8 more
doaj   +1 more source

Estrogen Induces Metastatic Potential of Papillary Thyroid Cancer Cells through Estrogen Receptor α and β

International Journal of Endocrinology, 2013
Estradiol (E2) promotes metastatic propensity. However, the detailed mechanism remains largely unknown. E-cadherin, vimentin, and MMP-9 play a dominant role in the metastatic process.
Wenwu Dong, Hao Zhang, Jing Li, Haixia Guan, Liang He, Zhihong Wang, Zhongyan Shan, Weiping Teng   +7 more
doaj   +1 more source

A framework for safe estradiol modulation in male bipolar disorder: theoretical justification for SERM-enabled adjunctive therapy

Frontiers in Psychiatry
Treatment-resistant bipolar disorder (TR-BD) in males remains a significant clinical challenge, often unresponsive to standard monoaminergic therapies.
John Carlson
doaj   +1 more source

17β-Estradiol and/or estrogen receptor alpha signaling blocks protein phosphatase 1 mediated ISO induced cardiac hypertrophy. [PDF]

PLoS ONE, 2018
Earlier studies have shown that estrogen possess protective function against the development of pathological cardiac hypertrophy. However, the molecular mechanisms of estrogens (E2) protective effect are poorly understood.
Hsin-Yuan Fang, Meng-Yu Hung, Yueh-Min Lin, Sudhir Pandey, Chia-Chien Chang, Kuan-Ho Lin, Chia-Yao Shen, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huang   +9 more
doaj   +1 more source

A case-matched comparison of ER-α and ER-β expression between malignant and benign cystic pancreatic lesions

Oncologie
Older studies failed to establish a link between estrogen receptor (ER) expression and pancreatic adenocarcinoma, with findings either statistically insignificant or contradictory. The recent discovery of two distinct isoforms, namely ER-α and ER-β, with
Lykoudis Panagis M., Papaconstantinou Ioannis, Dafnios Nikolaos, Charalampous Charalampos M., Konti Charis, Vlachodimitropoulos Dimitrios, Contis John   +6 more
doaj   +1 more source

Neuroprotective Effects of Genistein in Mongolian Gerbils: Estrogen Receptor–β Involvement

Journal of Pharmacological Sciences, 2010
Genistein is a naturally occurring plant-derived phytoestrogen, present in the human diet, known to possess some beneficial effects. The present study investigated the effect of genistein on neuroprotection evaluated through electroencephalographic and ...
Andrea Donzelli, Daniela Braida, Annamaria Finardi, Valeria Capurro, Anna Elisa Valsecchi, Mariapia Colleoni, Mariaelvina Sala   +6 more
doaj   +1 more source

Evaluating the Role of TGF Beta and TGF Beta Type 2 Receptor Along with p53 in Breast Cancer: A Cross-sectional Study from a Tertiary Care Centre of Eastern India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Immunohistochemical study of different markers is crucial now-a-days for molecular classification and study prognosis of breast cancer cases.
Palash K Mandal, Anindya Adhikari, Subrata Pal, Kaushik Dey, Subir Biswas, Aditi Sarkar   +5 more
doaj   +1 more source

Maximizing Production of Estrogen Receptor β with the Baculovirus Expression System

BioTechniques, 2003
Steroid hormone/nuclear receptor expression in cultured insect cell lines is routinely driven by a baculovirus vector. An advantage of the baculovirus production of these receptors is that large amounts of functional receptors are obtained for subsequent
Peter C. Kulakosky, Carolyn M. Klinge
doaj   +1 more source