Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers [PDF]
Introduction: We examined if a combination of proliferation markers and estrogen receptor (ER) activity could predict early versus late relapses in ER-positive breast cancer and inform the choice and length of adjuvant endocrine therapy.
Luca Gianni +39 more
core +2 more sources
Additional file 2. Figure S1: Genes regulated by either Esrrb or Hh-signaling pathway. Figure S2: Decision tree model of gene sorting. Figure S3: Hh-responsive transcription-related genes. Figure S4: Correlation of qPCR and RNA-seq of top 15 Hh differentially responsive genes. Figure S5: Esrrb-dependent Hh-responsive genes.
Lu, Yuan +3 more
openaire +1 more source
This study aimed to investigate the effects of Estrogen receptor β (ERβ) on osteosarcoma cells, and explore the regulatory mechanisms involved in this process. Osteosarcoma U2-OS cells consisted four groups, and treated by E2, E2 + LY294002 (ERβ agonists), E2 + ERβ siRNA, E2 + ERβ siRNA + LY294002, respectively.
Minfei Yang +4 more
openaire +3 more sources
Estrogen inhibits renal cell carcinoma cell progression through estrogen receptor-β activation. [PDF]
Renal cell carcinoma (RCC) originates in the lining of the proximal convoluted tubule and accounts for approximately 3% of adult malignancies. The RCC incidence rate increases annually and is twofold higher in males than in females.
Cheng-Ping Yu +8 more
doaj +1 more source
Table S1 Primers used for RT-qPCR analyses. (DOCX 14 kb)
Treeck, Oliver +4 more
openaire +1 more source
Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
Arturo Londono-Vallejo +55 more
core +2 more sources
Antibodies used in this study. (DOCX 12 kb)
SchĂźler-Toprak, Susanne +4 more
openaire +1 more source
Estrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats [PDF]
The ovarian hormone 17β-estradiol is known to regulate the release, expression and immunoreactivity of arginine-vasopressin (AVP) in the supraoptic and paraventricular hypothalamic nuclei of rodents.
Collado, Paloma +8 more
core +1 more source
Oxytocin and Estrogen Receptor β in the Brain: An Overview
Oxytocin is a neuropeptide synthesized primarily by neurons of the paraventricular and supraoptic nuclei of the hypothalamus. These neurons have axons that project into the posterior pituitary and release oxytocin into the bloodstream to promote labor ...
Alexandra eAcevedo-Rodriguez +2 more
doaj +1 more source
Estrogen receptor β agonist inhibits proliferation of endometrial stromal cells in an estrogen-receptor independent manner [PDF]
The finding that estrogen receptor ERβ agonists induce regression of ectopic endometrial implants in a rodent model has rekindled interest in the role of ERβ in the growth and maintenance of human endometriosis.
Xia Qiong, Zhao Dong, Wang Juan
doaj +1 more source

