Results 201 to 210 of about 90,675 (307)

Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet-Induced Adipose Tissue Inflammation. [PDF]

J Endocr Soc
Hope MC, Unger CA, Kettering MC, Socia CE, Aladhami AK, Rice BC, Niamira DS, Wiznitzer BP, Altomare D, Cotham WE, Enos RT.   +10 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

Novel Tetrahydrocyclohepteneindole Derivatives Targeting Estrogen Receptor Alpha for the Treatment of Breast Cancer. [PDF]

ACS Med Chem Lett
Song Z, Liang SH.
europepmc   +1 more source

Propofol‐induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This study aimed to assess the incidence and identify risk factors associated with the development of propofol‐induced hypertriglyceridemia in critically ill trauma patients who required nutrition therapy. Methods Adult patients (aged >17 years) admitted to the trauma intensive care unit who received propofol for >24 h and had a ...
Emma S. Lemke, Jonathon K. Walker, Julie E. Farrar, Saskya Byerly, Dina M. Filiberto, Roland N. Dickerson   +5 more
wiley   +1 more source

Androgen receptor antagonist flutamide modulates estrogen receptor alpha expression in distinct regions of the hypospadiac rat penis. [PDF]

Front Endocrinol (Lausanne)
Elmelund E, Draskau MK, Berg M, Strand IW, Black JR, Axelstad M, Pask AJ, Svingen T.   +7 more
europepmc   +1 more source

Estradiol replacement attenuates alendronate‐associated adverse effects on alveolar bone repair in ovariectomized rats

Journal of Periodontology, EarlyView.
Abstract Background Sodium alendronate (ALN) is widely used to treat postmenopausal osteoporosis, but both estrogen deficiency and antiresorptive therapy may impair alveolar bone repair after tooth extraction. A clinically relevant but insufficiently explored scenario involves estrogen‐deficient individuals receiving hormone replacement therapy (HRT ...
Pedro H. C. Isaias, Paulo G. B. Silva, Isabelly V. do Nascimento, Raul A. D. A. da Silva, Thayla M. do C. Sousa, Ana J. A. de de Vasconcelos, José V. M. Lemos, Fabrício B. Sousa, Ana P. N. N. Alves, Mário R. L. Mota   +9 more
wiley   +1 more source

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM's regulatory scientific confidence framework. [PDF]

Front Toxicol
Ryman J, Becker RA.
europepmc   +1 more source

Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright, Matthew G. Macowan, Keyuan Tian, Tracy Fitzsimmons, Rebecca L. Wilson, Claire T. Roberts, Claus T. Christophersen, Peter M. Bartold, Stephen P. Kidd, Peter S. Zilm   +9 more
wiley   +1 more source

Estradiol (E2) concentration shapes the chromatin binding landscape of estrogen receptor alpha. [PDF]

J Biol Chem
Han AL, Vinod Paul K, Rao S, Brechbuhl HM, Sartorius CA, Ramachandran S, Kabos P.   +6 more
europepmc   +1 more source

Improving nutritional assessment in pediatric anorexia nervosa: Clinical value of key serum biomarkers

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Reliable biochemical markers of starvation are needed to improve detection and monitoring of starvation in pediatric anorexia nervosa (AN), thus we explored new and revisited old potential serum biochemical markers. Methods In this prospective cohort study we included 65 pediatric patients with AN.
Ante Vidović, Nora Nikolac Gabaj, Barbara Perše, Marina Galešić, Magdalena Kršić, Sara Mašković, Matej Mustapić, Rea Takač, Orjena Žaja   +8 more
wiley   +1 more source