Results 221 to 230 of about 121,912 (288)

Breast Cancer: Habitat imaging based on intravoxel incoherent motion for predicting pathologic complete response to neoadjuvant chemotherapy

Medical Physics, EarlyView.
Abstract Background Radiomics research based on whole tumors is limited by the unclear biological significance of radiomics features, which therefore lack clinical interpretability. Purpose We aimed to determine whether features extracted from subregions defined by habitat imaging, reflecting tumor heterogeneity, could identify breast cancer patients ...
Hui Zhang, Yunyan Zheng, Mingzhe Zhang, Ailing Wang, Yang Song, Chenglong Wang, Guang Yang, Mingping Ma, Muzhen He   +8 more
wiley   +1 more source

Female mice lacking membrane estrogen receptor alpha display impairments in spatial memory. [PDF]

Horm Behav
DeLarge AF, Stanley MJ, Daniel JM.
europepmc   +1 more source

Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases

Neuroprotection, EarlyView.
The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide, Omamuyovwi M. Ijomone   +1 more
wiley   +1 more source

RNA fine-tunes estrogen receptor-alpha binding on low-affinity DNA motifs for transcriptional regulation. [PDF]

EMBO J
Soota D, Saravanan B, Mann R, Kharbanda T, Notani D.   +4 more
europepmc   +1 more source

Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines [PDF]

, 2003
DG Monroe, Steven A. Johnsen, Malayannan Subramaniam, B. Getz, Sundeep Khosla, B. Lawrence Riggs, TC Spelsberg   +6 more
openalex   +1 more source

Sex‐specific white matter alterations in children exposed to high pregestational BMI

Obesity, EarlyView.
Abstract Objective This study investigated whether exposure to high pregestational BMI (≥ 25 kg/m2) is associated with alterations in white matter microstructure in early childhood, explored sex‐specific effects, and examined associations with cognitive performance. Methods A total of 90 children from the Alberta Pregnancy Outcomes and Nutrition (APrON)
Samson Nivins, Jess Reynolds, Gerald F. Giesbrecht, Deborah Dewey, Nicole Letourneau, Catherine Lebel   +5 more
wiley   +1 more source

Progress in Aptamer Research and Future Applications

ChemistryOpen, EarlyView.
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu, Xiaolu Li, Huyang Gao, Jing Chen, Hongfeng Jiang   +4 more
wiley   +1 more source

Association of Inflammation and Immune Cell Infiltration with Estrogen Receptor Alpha in an Estrogen and Ionizing Radiation-Induced Breast Cancer Model. [PDF]

Int J Mol Sci
Koning T, Calaf GM.
europepmc   +1 more source

ADA3-containing complexes associate with estrogen receptor alpha

, 2002
Arndt Benecke, Claudine Gaudon Plesse, Jean‐Marie Garnier, Elmar vom Baur, Pierre Chambon, Régine Losson   +5 more
openalex   +1 more source

Investigation of a Radio-Iodinated Alpha-Mangostin for Targeting Estrogen Receptor Alpha (ERα) in Breast Cancer: In Silico Design, Synthesis, and Biological Evaluation. [PDF]

Drug Des Devel Ther
Muchtaridi M, Nurhidayah W, Fakih TM, Kannaka K, Suzuki H, Subroto T, Uehara T.   +6 more
europepmc   +1 more source