Results 231 to 240 of about 121,912 (288)

Treatment strategy for systemic lupus erythematosus using belimumab as indicated by multi‐omics analysis

Rheumatology &Autoimmunity, EarlyView.
Recent multi‐omics studies have demonstrated that belimumab specifically targets naïve B cells and a subset of memory B cells. This observation is consistent with belimumab's established efficacy and safety profile. Abstract Belimumab is an antibody targeting the cytokine B‐cell activating factor (BAFF), which is crucial for B cell differentiation, and
Keishi Fujio, Toshiyuki Ushijima, Tatsuki Abe, Tomohisa Okamura, Sang‐Cheol Bae, Yumi Tsuchida   +5 more
wiley   +1 more source

The Lysine Acetyltransferase PCAF Functionally Interacts with Estrogen Receptor Alpha in the Hippocampus of Gonadally Intact Male-But Not Female-Rats to Enhance Short-Term Memory. [PDF]

J Neurosci
Mitchnick KA, Nicholson K, Wideman C, Jardine K, Jamieson-Williams R, Creighton SD, Lacoursiere A, Milite C, Castellano S, Sbardella G, MacLusky NJ, Choleris E, Winters BD.   +12 more
europepmc   +1 more source

Estrogen receptor-alpha and -beta expression in microvascular endothelial cells and smooth muscle cells of myometrium and leiomyoma

, 2002
Caroline E. Gargett
openalex   +1 more source

Localized Microrobotic Delivery of Enzyme‐Responsive Hydrogel‐Immobilized Therapeutics to Suppress Triple‐Negative Breast Cancer

Small, EarlyView.
In response to enzymatic activity within the tumor microenvironment, remotely actuated microrobots designed for localized delivery of stimuli‐responsive hydrogels engineered to release chemotherapeutics (ChemoBots) are developed. The system leverages magnetic navigation for targeted localization and prolongsed drug release, achieving marked tumor ...
Mingzhen Tian, Meysam Keshavarz, Ali Anil Demircali, Bing Han, Guang‐Zhong Yang   +4 more
wiley   +1 more source

Hepatic estrogen receptor alpha drives masculinization in post-menopausal women with metabolic dysfunction-associated steatotic liver disease. [PDF]

JHEP Rep
Meda C, Benedusi V, Cherubini A, Valenti L, Maggi A, Della Torre S.   +5 more
europepmc   +1 more source

Micro/Nanorobotics in Environmental Water Governance: Nanoengineering Strategies for Pollution Control

Small Structures, EarlyView.
Micro/nanorobots have been developed and deployed, revealing their state‐of‐the‐art applications in pollution detection and remediation. Innovative research progress includes collective behaviors, advanced propulsion mechanisms, and functionalization strategies that enhance their efficiency in diverse and complex aquatic environments, pointing toward ...
Yingyi Gan, Bin Wang, Yuan Lu
wiley   +1 more source

Endosomal recycling inhibitors downregulate estrogen receptor-alpha and synergise with endocrine therapies. [PDF]

Breast Cancer Res Treat
Fletcher KA, Alkurashi MH, Lindsay AJ.
europepmc   +1 more source

Citrus polymethoxyflavones degrade estrogen receptor-alpha (ERα) and combine with tamoxifen for the treatment of estrogen receptor-positive breast cancer. [PDF]

Heliyon
Wang Y, Sun M, He Z, Han Y, Song Y, Liang J, Wang H, Qin Y, Deng Z.   +8 more
europepmc   +1 more source

Laryngopharyngeal Reflux: The Impact of Obesity

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan, Mary J. Hawkshaw, Robert T. Sataloff   +2 more
wiley   +1 more source

The Relationship between Time, Race, and Estrogen Receptor Alpha in Estradiol-Induced Dermal Fibrosis. [PDF]

Biomedicines
Baker Frost D, Savchenko A, Feghali-Bostwick C, Wolf B.   +3 more
europepmc   +1 more source