Results 231 to 240 of about 80,501 (258)
Some of the next articles are maybe not open access.
Nutritional flavonoids modulate estrogen receptor alpha signaling.
IUBMB life, 2004Estrogen receptor alpha (ERalpha) mediates 17beta-estradiol (E2) actions through the transcription of E2-sensitive target genes. In addition, rapid non-genomic signaling (e.g., MAPK/ERK) occurs. It is now well accepted that these rapid membrane-initiated responses account for E2-related cancer.
Virgili F +5 more
openaire +4 more sources
Acta Histochemica, 2004
The endometrium expresses estrogen (ER) and progesterone receptors (PR), which are involved in autocrine and paracrine regulation processes in response to estrogen and progesterone. The aim of the present study was to evaluate immunohistochemical distribution patterns of estrogen receptor alpha (ER alpha), estrogen receptor beta (ER beta) and PR in ...
Ioannis, Mylonas +7 more
openaire +2 more sources
The endometrium expresses estrogen (ER) and progesterone receptors (PR), which are involved in autocrine and paracrine regulation processes in response to estrogen and progesterone. The aim of the present study was to evaluate immunohistochemical distribution patterns of estrogen receptor alpha (ER alpha), estrogen receptor beta (ER beta) and PR in ...
Ioannis, Mylonas +7 more
openaire +2 more sources
Cancer Research, 2011
Abstract Introduction: Alcohol consumption is an established risk factor for breast cancer development and contributes to mammary tumorigenesis through the regulation of estrogen receptor alpha (ERα) expression. Previously, we reported that alcohol consumption in the MMTV-neu ERα-negative mouse model of human breast cancer resulted in ...
AW Wong, N Nunez
openaire +1 more source
Abstract Introduction: Alcohol consumption is an established risk factor for breast cancer development and contributes to mammary tumorigenesis through the regulation of estrogen receptor alpha (ERα) expression. Previously, we reported that alcohol consumption in the MMTV-neu ERα-negative mouse model of human breast cancer resulted in ...
AW Wong, N Nunez
openaire +1 more source
Binding studies on estrogen receptor alpha
2009Die wachsende Anzahl an charakterisierten molekularen Rezeptoren liefert die Basis für das struktur-basierte Design von aktiven Verbindungen zur Entwicklung eines neuen Medikamentes. Ausgehend von einer bekannten oder hypothetischen Wirkungsweise oder einem Bindungsmechanismus wird eine vernünftige Vorlage entworfen, die später experimentell getestet ...
openaire +1 more source
Cancer research, 2001
4-Hydroxytamoxifen (4-OHT), a selective estrogen receptor modulator, is an agonist at a transforming growth factor-alpha (TGF-alpha) target gene in situ in MDA-MB-231 human breast cancer cells stably transfected with wild-type human ERalpha. In contrast, raloxifene (Ral) is a complete antiestrogen silencing activation function (AF) 1 and AF2 in this ...
H, Liu +4 more
openaire +1 more source
4-Hydroxytamoxifen (4-OHT), a selective estrogen receptor modulator, is an agonist at a transforming growth factor-alpha (TGF-alpha) target gene in situ in MDA-MB-231 human breast cancer cells stably transfected with wild-type human ERalpha. In contrast, raloxifene (Ral) is a complete antiestrogen silencing activation function (AF) 1 and AF2 in this ...
H, Liu +4 more
openaire +1 more source
Estrogen receptor-related receptor-alpha (ERR-alpha) is dysregulated in inflammatory arthritis.
Rheumatology (Oxford, England), 2008Subchondral bone loss is a characteristic feature of inflammatory arthritis. Recently, estrogen receptor-related receptor-alpha (ERR-alpha), an orphan nuclear receptor, has been found to be involved in activation of macrophages. We hypothesized that ERR-alpha which is expressed and also functional in articular chondrocytes, osteoblasts and osteoclasts,
E, Bonnelye +4 more
openaire +1 more source
A review of cancer immunotherapy toxicity
Ca-A Cancer Journal for Clinicians, 2020Lucy Boyce Kennedy
exaly
Role of estrogen receptor beta in epithelia lacking estrogen receptor alpha expression
2008Estrogens influence the physiology of many organs by activation of the nuclear receptors ERalpha and ERbeta. The epithelium of ventral prostate, ovarian granulosa cells and lung, are ERalpha-negative but express high levels of ERbeta. This thesis focuses on the role played by ERbeta in ERalpha-negative epithelium. The prostate is of medical interest
openaire +1 more source
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly