Results 51 to 60 of about 2,702,960 (399)
The roles of estrogen and estrogen receptors in gastrointestinal disease.
Oncology Letters, 2019 Estrogen is an important sex steroid hormone which serves an important role in the regulation of a number of biological functions, including regulating bone density, brain function, cholesterol mobilization, electrolyte balance, skin physiology, the ...
Changmei Chen +8 more
semanticscholar +1 more source
Phytochemicals Targeting Estrogen Receptors: Beneficial Rather Than Adverse Effects?
International Journal of Molecular Sciences, 2017 In mammals, the effects of estrogen are mainly mediated by two different estrogen receptors, ERα and ERβ. These proteins are members of the nuclear receptor family, characterized by distinct structural and functional domains, and participate in the ...
S. Lecomte +3 more
semanticscholar +1 more source
Local estrogen formation and its regulation in endometriosis
Reproductive Medicine and Biology, 2019 Background It has been well established that endometriosis is an estrogen‐dependent disease. Although the exact pathogenesis of the disease is still unclear, it is known to be characterized by estrogen‐dependent growth and maintenance of the ectopic ...
Taisuke Mori +7 more
doaj +1 more source
The binding of estrogen and estrogen antagonists to the estrogen receptor
Archives of Biochemistry and Biophysics, 1992 The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
Shlomo Sasson +2 more
openaire +3 more sources
The Serine/Threonine Protein Kinase (Akt)/ Protein Kinase B (PkB) Signaling Pathway in Breast Cancer [PDF]
, 2020 According to statistical data published in 2019, breast cancer is among the leading causes of death in women worldwide. The serine/threonine kinase (AKT) or protein kinase B (PkB) signaling pathway is activated by phosphorylation processes, which further
Bratu, Ovidiu Gabriel +8 more
core +3 more sources
Molecular Imaging Provides Novel Insights on Estrogen Receptor Activity in Mouse Brain
Molecular Imaging, 2008 Estrogen receptors have long been known to be expressed in several brain areas in addition to those directly involved in the control of reproductive functions.
Alessia Stell +3 more
doaj +1 more source
Silibinin protects GLUTag cells from PA-induced injury via suppressing endoplasmic reticulum stress
CyTA - Journal of Food, 2023 Silibinin is a natural flavonoid with anti-diabetic activity. Glucagon-like peptide−1 (GLP−1), an intestinal hormone mainly secreted from L cells, which regulates insulin production and sensitivity, appears to be a potential therapeutic strategy for T2DM.
Xinyi Shi +9 more
doaj +1 more source
Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]
, 2010 Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B. +3 more
core +2 more sources
Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line
Research in Pharmaceutical Sciences, 2018 Estrogen is a steroid hormone that plays a key role in the development and regulation of reproductive system. It has been shown that estrogen is related to breast cancer development through binding to its receptors.
Azam Mohamadi +2 more
doaj +1 more source
BMC Biology, 2022 Background Estriol (E3) is a steroid hormone formed only during pregnancy in primates including humans. Although E3 is synthesized at large amounts through a complex pathway involving the fetus and placenta, it is not required for the maintenance of ...
Yuping Zhou +13 more
doaj +1 more source