Results 51 to 60 of about 2,557,731 (353)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
PLoS ONE, 2013 Two major breast cancer sub-types are defined by the expression of estrogen receptors on tumour cells. Cancers with large numbers of receptors are termed estrogen receptor positive and those with few are estrogen receptor negative.
Rosanna Upstill-Goddard +6 more
doaj +1 more source
The Professional Medical Journal, 2018 Objectives: Purpose of study is to determine Estrogen receptor status ininflammatory and neoplastic lesions of human gallbladder and to determine any relation ofER status with age, sex and histological grades of gallbladder carcinoma.
M. Shah +5 more
semanticscholar +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Analysis of study rezults of biopsies of the vagina mucous membrane in women with recurrent genital prolapse. [PDF]
Medičnì Perspektivi, 2014 The study involved 53 women with recurrent genital prolapse. The average age of the women studied was 62,8±9,8 years, age of women of the control group was 57,2±6,3 years (p>0,05).
R. M. Banakhevich +3 more
doaj +2 more sources
Expression of estrogen and progesterone receptors in astrocytomas: a literature review
ClinicsGliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones.
Cléciton Braga Tavares +11 more
doaj +1 more source
The estrogen receptor and metabolism
Women's HealthAcross the globe, metabolic syndrome, hyperuric acid, and their related diseases, such as cardiovascular disease, diabetes, and insulin resistance, are increasing in incidence due to metabolic imbalances. Due to the pathogenesis, women are more prone to these diseases than men.
Zizi Xiao, Haijun Liu
openaire +3 more sources
Estrogen-Independent Activation of Estrogen Receptors [PDF]
Hypertension, 2011 See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer +2 more
openaire +3 more sources
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Estrogens and the risk of breast cancer: A narrative review of literature
Heliyon, 2023 In female mammals, the development and regulation of the reproductive system and non-reproductive system are significantly influenced by estrogens (oestrogens). In addition, lipid metabolism is another physiological role of estrogens.
Khayry Al-Shami +10 more
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