Results 61 to 70 of about 2,702,960 (399)

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Estrogen modulation of pain perception with a novel 17β-estradiol pretreatment regime in ovariectomized rats

Biology of Sex Differences, 2020
Estrogen plays substantial roles in pain modulation; however, studies concerning sex hormones and nociception often yield confusing results. The discrepancy could be a result of lack of consensus to regard estrogen as a variable when working with animal ...
Wenxin Zhang, Hui Wu, Qi Xu, Sheng Chen, Lihong Sun, Cuicui Jiao, Luyang Wang, Feng Fu, Ying Feng, Xiaowei Qian, Xinzhong Chen   +10 more
doaj   +1 more source

Ageing And Cancer As Diseases Of Epigenesis [PDF]

, 2009
Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core   +2 more sources

Estradiol and testosterone levels in patients undergoing partial hepatectomy - A possible signal for hepatic regeneration? [PDF]

, 1989
In five adult male patients undergoing a 40-60% partial hepatectomy, serum sex hormone levels before and after hepatic resection were determined. Blood was drawn immediately prior to each surgical procedure and at specified time points postoperatively ...
A Francavilla, A Francavilla, A Francavilla, A Francavilla, B Fisher, B Saint Aubert, C Majumdar, CS Song, DH Marshall, FL Moolten, HL Leffert, I Seidman, IF Turocy, J Menard, J Simck, J Simck, JA Caruana, JC Davis, JH Laragh, K Sakuma, KH Raab, LE Porter, MJ Duffy, NLR Bucher, NLR Bucher, P Bannister, P Vic, PK Eagon, PK Eagon, PL Corvol, RA Richman, RF Aten, S Bengmark, S Bengmark, W Powell-Jones   +34 more
core   +2 more sources

Estrogen metabolism: why it’s so crucial to keep the balance?

Гинекология, 2020
Aim. To analyze and systematize the available information on pathogenetic mechanisms of hormonal carcinogenesis. Materials and methods. The review includes data from foreign articles published in PubMed and Medline and national works posted on ...
Oksana V. Yakushevskaya, Svetlana V. Yureneva, Anna E. Protasova   +2 more
doaj   +1 more source

Endocrine Disruptors Acting on Estrogen and Androgen Pathways Cause Reproductive Disorders through Multiple Mechanisms: A Review

International Journal of Environmental Research and Public Health, 2021
Increasing contamination of the environment by toxic compounds such as endocrine disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both sexes.
S. Amir, S. T. Shah, C. Mamoulakis, A. Docea, O. Kalantzi, A. Zachariou, D. Calina, F. Carvalho, N. Sofikitis, A. Makrigiannakis, A. Tsatsakis   +10 more
semanticscholar   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

Placental weight and mortality in premenopausal breast cancer by tumor characteristics [PDF]

, 2013
Placental weight may be regarded as an indirect marker of hormone exposures during pregnancy. There is epidemiological evidence that breast cancer mortality in premenopausal women increases with placental weight in the most recent pregnancy.
Adolfsson, J., Bahmanyar, S., Cnattingius, S., Fornander, T., Hajiebrahimi, M.H., Lambe, M., Wärnberg, F.   +6 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Support Vector Machine classifier for estrogen receptor positive and negative early-onset breast cancer.

PLoS ONE, 2013
Two major breast cancer sub-types are defined by the expression of estrogen receptors on tumour cells. Cancers with large numbers of receptors are termed estrogen receptor positive and those with few are estrogen receptor negative.
Rosanna Upstill-Goddard, Diana Eccles, Sarah Ennis, Sajjad Rafiq, William Tapper, Joerg Fliege, Andrew Collins   +6 more
doaj   +1 more source