Results 81 to 90 of about 2,702,960 (399)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Expression of estrogen and progesterone receptors in astrocytomas: a literature review
ClinicsGliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones.
Cléciton Braga Tavares +11 more
doaj +1 more source
Estrogen-Related Receptors in Breast Cancer and Prostate Cancer
Frontiers in Endocrinology, 2015 Estrogen signaling pathways are implicated in the development of breast cancer and prostate cancer. Various studies have focused on additional signaling pathways, mediated by estrogen-related receptors (ERRs).
Satoshi eInoue +2 more
doaj +1 more source
Molecules, 2021 Flavonoids are plant bioactives that are recognized as hormone-like polyphenols because of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their estrogen- and androgen-like activity. Most efforts to verify flavonoid
Giulia D’Arrigo +5 more
doaj +1 more source
Estrogen Receptors and Their Implications in Colorectal Carcinogenesis
Frontiers in Oncology, 2015 Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate intracellular signaling cascades that have important consequences for cellular behavior. Historically linked to carcinogenesis in reproductive organs, estrogens have also
F. Caiazza +4 more
semanticscholar +1 more source
Estrogen-Independent Activation of Estrogen Receptors [PDF]
Hypertension, 2011 See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer +2 more
openaire +3 more sources
Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]
, 2003 Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi +5 more
core +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Analysis of study rezults of biopsies of the vagina mucous membrane in women with recurrent genital prolapse. [PDF]
Medičnì Perspektivi, 2014 The study involved 53 women with recurrent genital prolapse. The average age of the women studied was 62,8±9,8 years, age of women of the control group was 57,2±6,3 years (p>0,05).
R. M. Banakhevich +3 more
doaj +2 more sources
Estrogen Actions in Triple-Negative Breast Cancer
Cells, 2020 Triple-negative breast cancer (TNBC) lacks estrogen receptor (ER) α, but the expression of estrogen receptors ERβ and G protein-coupled estrogen receptor 1 (GPER-1) is able to trigger estrogen-responsivity in TNBC.
Oliver Treeck +2 more
doaj +1 more source