Results 101 to 110 of about 163,959 (310)

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

The GABAergic system: a possible component of estrogenic feedback on gonadotropin secretion in rainbow trout (Oncorhynchus mykiss)

Knowledge and Management of Aquatic Ecosystems, 1998
In teleost fish, GTH secretion is controlled by a large number of neuroendocrine factors at the central level and steroid feedback represents an efficient process to synchronize the activity of all the systems involved along the brain-pituitary-gonad ...
ANGLADE I., DOUARD V., LE JOSSIC-CORCOS C., MANANOS E. L., MAZURAIS D., MICHEL D., KAH O.   +6 more
doaj   +1 more source

Unravelling the mechanism of differential biological responses induced by food-borne xeno- and phyto-estrogenic compounds

, 2010
The multiple actions of estradiol and other estrogenic compounds in mammalian physiology are brought about, on a molecular level, as a result of complex signalling pathways, and mediated by at least two receptors namely estrogen receptor (ER) α and ERβ.
Sotoca Covaleda, A.M.
core  

Shell formation and bone strength in laying hens [PDF]

, 2013
In Sweden almost 3.8% of all eggs are ruined due to cracked eggshells as shell quality declines with age during the laying period. This is a concern for food safety as well as an economical problem.
Wistedt, Anna
core  

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Molecular characterization and expression profile of estrogen receptor subtypes in female hilsa (Tenualosa ilisha)

Frontiers in Marine Science
Hilsa (Tenualosa ilisha), a highly prized edible fish, is consumed by over 250 million people worldwide. Estrogens are essential hormones required during reproduction and bind with estrogen receptors in target organs for biological activity.
Arpita Roy, Arpita Roy, Vikash Kumar, Kampan Bisai, Pratyasha Bhowal, Soumya Prasad Panda, Asim Kumar Jana, Rajat Banerjee, Basanta Kumar Das   +8 more
doaj   +1 more source

Understanding the role of estrogen in the development of benign prostatic hyperplasia

African Journal of Urology, 2018
Introduction: Benign prostatic hyperplasia (BPH) is a non-malignant enlargement of the prostate that affects ageing men. As the number of men affected by this condition will only continue to grow with the aging population, finding new strategies and new ...
A. Ajayi, K. Abraham
doaj   +1 more source

Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997 [PDF]

, 2009
Using archived tumours, those from 1984-1986 and 1996-1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices,
Cooke, T.G., F M Campbell, Mallon, E.A., Brown, S.B.F., Elsberger, B., T G Cooke, L M McGlynn, McGlynn, L.M., B Elsberger, S B F Brown, E A Mallon, Campbell, F.M., J Edwards, Edwards, J.   +13 more
core   +1 more source

The estrogen receptor and metabolism

Women's Health
Across the globe, metabolic syndrome, hyperuric acid, and their related diseases, such as cardiovascular disease, diabetes, and insulin resistance, are increasing in incidence due to metabolic imbalances. Due to the pathogenesis, women are more prone to these diseases than men.
Zizi Xiao, Haijun Liu
openaire   +3 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source