Outer Membrane Vesicles From Bacteroides fragilis Contain Coding and Non‐Coding Small RNA Species That Modulate Inflammatory Signalling in Intestinal Epithelial Cells [PDF]
Alterations to the community structure and function of the microbiome are associated with changes to host physiology, including immune responses. However, the contribution of microbe‐derived RNAs carried by outer membrane vesicles (OMVs) to host immune ...
Aadil Sheikh +20 more
doaj +3 more sources
Carbapenem resistance in enterotoxigenic Bacteroides fragilis isolated from colonoscopy candidates [PDF]
The present study aimed to determine the carbapenem resistance among Enterotoxigenic Bacteroides fragilis (ETBF) isolated from patients candidates to colonoscopy in Shiraz, Iran. A total of 201 stool samples were gathered from 201 patients. The detection
Narges Nasoohian +4 more
doaj +2 more sources
Biological Mechanisms of Enterotoxigenic Bacteroides fragilis Toxin: Linking Inflammation, Colorectal Cancer, and Clinical Implications [PDF]
Enterotoxigenic Bacteroides fragilis (ETBF) has emerged as a gut microbiome pathogen that can promote intestinal inflammation and contribute to colorectal cancer (CRC).
Seyedesomaye Jasemi +5 more
doaj +2 more sources
Prevalence of enterotoxigenic Bacteroides fragilis in patients with colorectal cancer: a systematic review and meta-analysis [PDF]
IntroductionThe gut microbiome, specifically enterotoxigenic Bacteroides fragilis (ETBF), has been reported to play a role in colorectal cancer development.
Shijun Xia +4 more
doaj +2 more sources
The Ambivalent Nature of Bacteroides fragilis and the Interaction with Clostridioides difficile: Benefits and Disadvantages for the Human Host [PDF]
Bacteroides fragilis is a usually beneficial colonizer of the human gut that can also act as an opportunistic pathogen, causing infection and contributing to the development and progression of important diseases.
Patrizia Spigaglia
doaj +2 more sources
Caffeic Acid Phenethyl Ester Administration Reduces Enterotoxigenic Bacteroides fragilis-Induced Colitis and Tumorigenesis [PDF]
The human colonic commensal enterotoxigenic Bacteroides fragilis (ETBF) is associated with chronic colitis and colon cancer. ETBF colonization induces colitis via the Bacteroides fragilis toxin (BFT).
Soonjae Hwang +7 more
doaj +2 more sources
Bacteroides fragilis Toxin Induces Sequential Proteolysis of E-Cadherin and Inflammatory Response in Mouse Intestinal Epithelial Cell Line [PDF]
Enterotoxigenic Bacteroides fragilis (ETBF) is an intestinal bacterium that secretes the metalloprotease Bacteroides fragilis toxin (BFT), which induces E-cadherin cleavage and interleukin-8 secretion in human intestinal epithelial cell lines.
Woo-Seung Kim +10 more
doaj +2 more sources
An enteropathogenic microbial toxin modulates the breast cancer epigenome resulting in concurrent silencing of tumor suppressor genes [PDF]
Background Recent studies have determined a close association between host microbiota and breast cancer initiation, growth and therapeutic outcomes.
Deepak Verma +4 more
doaj +2 more sources
The gut microbiome in colorectal cancer: mechanisms of carcinogenesis and emerging microbiota-targeted therapies [PDF]
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality globally. Beyond established genetic and environmental risk factors, the gut microbiome is now recognized as a pivotal contributor to CRC pathogenesis, progression, and ...
Yue Li +3 more
doaj +2 more sources
Gut microbiota and colorectal cancer: mechanistic insights, diagnostic advances, and microbiome-based therapeutic strategies [PDF]
Colorectal cancer (CRC) is closely linked to gut microbiota dysbiosis. We synthesize evidence that carcinogenic microbes promote CRC through chronic inflammation, bacterial genotoxins, and metabolic imbalance, highlighting key pathways involving ...
Bingbing Bai +59 more
doaj +2 more sources

