Background The association between specific bacteria and colorectal cancer (CRC) has been proposed. Only a few studies have, however, investigated this relationship directly in colorectal tissue with conflicting results.
Nasibeh Khodaverdi +4 more
doaj +1 more source
The tumor-microbe connection. [PDF]
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Vella G, Rescigno M.
europepmc +2 more sources
Comparison of Adipose Distribution Indices with Gold Standard Body Composition Assessments in the EMPA-REG H2H SU Trial: A Body Composition Sub-Study [PDF]
INTRODUCTION: Excess adiposity contributes to cardiometabolic disease. Although adipose depots can be measured using imaging, implementation remains limited in practice.
Björn Eliasson +7 more
core +1 more source
BackgroundEnterotoxigenic Bacteroides fragilis (ETBF) is a toxin-producing bacteria thought to possibly promote colorectal carcinogenesis by modulating the mucosal immune response and inducing epithelial cell changes.
Rachel V Purcell +5 more
doaj +1 more source
EnterotoxigenicBacteroides fragilis(ETBF)-mediated colitis in Min (Apc+/-) mice: a human commensal-based murine model of colon carcinogenesis [PDF]
Colorectal cancer (CRC) represents a common cancer worldwide and the fourth leading cause of cancer in the US with 150,000 new cases annually in the adult population.1 CRC is ultimately a genetic disease in which damaged DNA and genetic instability initiate malignant transformation.
Franck, Housseau, Cynthia L, Sears
openaire +2 more sources
IntroductionObesity, an independent risk factor for breast cancer growth and metastatic progression, is also closely intertwined with gut dysbiosis; and both obese state and dysbiosis promote each other.
Sheetal Parida +13 more
doaj +1 more source
Re-Examining Mortality Sources and Population Trends in a Declining Seabird: Using Bayesian Methods to Incorporate Existing Information and New Data [PDF]
The population of flesh-footed shearwaters (Puffinus carneipes) breeding on Lord Howe Island was shown to be declining from the 1970’s to the early 2000’s. This was attributed to destruction of breeding habitat and fisheries mortality in the Australian
Hindell, MA +3 more
core +2 more sources
Background Colorectal cancer (CRC) is the third most diagnosed cancer and the second most common cause of cancer deaths worldwide. CRC patients present with an increase in pathogens in their gut microbiota, such as polyketide synthase-positive bacteria ...
Manon Oliero +13 more
doaj +1 more source
Experimental study on the effect of bft toxin isolated and purified from clinical isolates of Enterotoxigenic Bacteroides fragilis on the liver, spleen and intestine of mice [PDF]
This study includes three parts: isolation of Enterotoxigenic Bacteroid fragilis from 94 stool samples collected from different hospitals in Baghdad city from the beginning of March/2020 to the end of April/2021.
Hussein Khaleefah, Ashwak Jasim
doaj +1 more source
The Emerging Role of Epigenetic Modifiers in Repair of DNA Damage Associated with Chronic Inflammatory Diseases [PDF]
At sites of chronic inflammation epithelial cells are exposed to high levels of reactive oxygen species (ROS), which can contribute to the initiation and development of many different human cancers.
Ding, Ning +2 more
core +1 more source

