Results 21 to 30 of about 5,945,207 (220)

The compromise of macrophage functions by hyperoxia is attenuated by ethacrynic acid via inhibition of NF-κB-mediated release of high-mobility group box-1. [PDF]

open access: yesAm J Respir Cell Mol Biol, 2015
Wang M   +11 more
europepmc   +2 more sources

Synthesis and Antiproliferative Activity of New Ruthenium Complexes with Ethacrynic-Acid-Modified Pyridine and Triphenylphosphine Ligands. [PDF]

open access: yesInorganic Chemistry, 2015
Pyridine- and phosphine-based ligands modified with ethacrynic acid (a broad acting glutathione transferase inhibitor) were prepared and coordinated to ruthenium(II)–arene complexes and to a ruthenium(III) NAMI-A type complex.
Gabriele Agonigi   +7 more
semanticscholar   +2 more sources

Loop Diuretics Inhibit Ischemia-Induced Intracellular Ca2+ Overload in Neurons via the Inhibition of Voltage-Gated Ca2+ and Na+ Channels

open access: yesFrontiers in Pharmacology, 2021
One consequence of ischemic stroke is disruption of intracellular ionic homeostasis. Intracellular overload of both Na+ and Ca2+ has been linked to neuronal death in this pathophysiological state.
Christopher Katnik, Javier Cuevas
doaj   +1 more source

mRNA Sequencing Reveals Upregulation of Glutathione S-Transferase Genes during Acanthamoeba Encystation

open access: yesMicroorganisms, 2023
Some members of the genus Acanthamoeba are facultative pathogens typically with a biphasic lifestyle: trophozoites and cysts. Acanthamoeba is capable of infecting the cornea, resulting in Acanthamoeba keratitis.
Alvaro de Obeso Fernández del Valle   +4 more
doaj   +1 more source

Glutathione S-Transferases Play a Crucial Role in Mitochondrial Function, Plasma Membrane Stability and Oxidative Regulation of Mammalian Sperm

open access: yesAntioxidants, 2020
Glutathione S-transferases (GSTs) are essential sperm antioxidant enzymes involved in cell protection against oxidative stress and toxic chemicals, preserving sperm function and fertilising ability.
Marc Llavanera   +8 more
doaj   +1 more source

Increased Resting-State Positron Emission Tomography Activity After Cochlear Implantation in Adult Deafened Cats [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2023
Objectives. Cochlear implants are widely used for hearing rehabilitation in patients with profound sensorineural hearing loss. However, Cochlear implants have variable results, and central neural plasticity is considered to be a reason for this ...
Min-Hyun Park   +4 more
doaj   +1 more source

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