Results 51 to 60 of about 5,945,207 (220)

Predictors of a Gabapentinoid–Loop‐Diuretic Prescribing Cascade in U.S. Nursing Home Residents

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 2, Page 336-344, February 2026.
Among 23,544 older adult long‐stay nursing home residents who initiated a gabapentinoid in the nursing home (2016–2022), 4.2% experienced a loop diuretic prescribing cascade within 90 days. Predictors of the prescribing cascade included older age, higher medication burden (≥ 15 medications), current receipt of non‐loop diuretics, and titration of ...
Kaleen N. Hayes   +7 more
wiley   +1 more source

Some effects of insect hormones on Na(^+), K(^+)-ATPase and fluid secretion by the malpighian tubules of locusta migratoria L [PDF]

open access: yes, 1981
A study has been made on the effects of insect hormones on fluid secretion by the Malpighian tubules of Locusta, and on the Na(^+), K(^+)- ATPase activity in microsomal preparations of the tubules.
Donkin, Julie Ellison
core  

Influence of ethacrynic acid on intrarenal renin release mechanisms

open access: yes, 1975
Influence of ethacrynic acid on intrarenal renin release mechanisms. Ethacrynic acid infused i.v. in anesthetized dogs after inhibiting sympathetic mechanisms of renin release increased renal blood flow rate (RBF) by 54% and practically abolished ...
Langård, Øivind   +3 more
core   +1 more source

Effects of ethacrynic acid on ion transport and energy metabolism in slices of avian salt gland and of mammalian liver and kidney cortex [PDF]

open access: yes, 1978
Ethacrynic acid greatly inhibited net transport of ions and aerobic, energyconserving metabolism in slices of avian salt gland, rat liver, and rat and guinea-pig kidney cortex.
Rossum, George D. V., Ernst, Stephen A.
core   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Design, Synthesis, and Evaluation of EA-Sulfonamides and Indazole-Sulfonamides as Promising Anticancer Agents: Molecular Docking, ADME Prediction, and Molecular Dynamics Simulations

open access: yesChemistry
New EA-sulfonamides and indazole-sulfonamides were synthesized, characterized, and evaluated for their anticancer activities. The target compound structures were elucidated using various spectroscopic techniques such as NMR-{1H and 13C}, infrared ...
Nassima Saghdani   +6 more
doaj   +1 more source

Biological significance of glutathione S-transferases in human sperm cells

open access: yesJournal of Human Reproductive Sciences, 2019
Background: Oxidative stress is considered as one of the causes of male subfertility or infertility. Among antioxidant enzymes, the crucial role belongs to glutathione S-transferases (GSTs).
Roman V Fafula   +6 more
doaj   +1 more source

Alpha-class glutathione S-transferases in wild turkeys (Meleagris gallopavo): characterization and role in resistance to the carcinogenic mycotoxin aflatoxin B1. [PDF]

open access: yesPLoS ONE, 2013
Domestic turkeys (Meleagris gallopavo) are one of the most susceptible animals known to the toxic effects of the mycotoxin aflatoxin B1 (AFB1), a potent human hepatocarcinogen, and universal maize contaminant.
Ji Eun Kim   +4 more
doaj   +1 more source

Effects of Isoproterenol, Diazoxide, Ethacrynic Acid, and Furosemide on Skeletal Muscle Vascular Resistance

open access: yes, 1973
The vasodilator properties of isoproterenol, diazoxide, ethacrynic acid, and furosemide were compared in the isolated canine gracilis muscle perfused with arterial blood at a constant rate.
R. I. Ogilvie, P. Larochelle, E. Mikulic
core   +1 more source

Characterization of Affinity-Purified Isoforms of Acinetobacter calcoaceticus Y1 Glutathione Transferases

open access: yesThe Scientific World Journal, 2014
Glutathione transferases (GST) were purified from locally isolated bacteria, Acinetobacter calcoaceticus Y1, by glutathione-affinity chromatography and anion exchange, and their substrate specificities were investigated.
Chin-Soon Chee   +2 more
doaj   +1 more source

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