Comparison of left ventricular diastolic function parameters in patients induced with propofol and etomidate: A randomized clinical trial [PDF]
Journal of Anaesthesiology Clinical PharmacologyBackground and Aims: Anesthetic agents like propofol and etomidate are known to affect intracellular calcium homeostasis during diastole. Hence, this study has been designed to study the effects of etomidate and propofol on left ventricular diastolic ...
Shanmugappriya Arunachalam +5 more
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Comparing the Impact of Metoclopramide versus Ondansetron on Pain Reduction Caused by Etomidate Injection in Patients under General Anesthesia [PDF]
Advanced Biomedical ResearchBackground: Etomidate is a short-acting intravenous anesthetic commonly used for induction of general anesthesia and sedation. Preventing pain caused by etomidate injection can improve patient comfort and broaden its clinical use. This study compared the
Zahra Rahimi +3 more
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The novel etomidate analog: A potential induction agent [PDF]
Saudi Journal of AnaesthesiaEtomidate is the agent of choice for the induction of anesthesia in patients with cardiovascular illness, hypotension, or shock. Notwithstanding its numerous attributes, etomidate’s most notable adverse impact is adrenocortical suppression.
Konica Chittoria, Ankur Sharma
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Etomidate-Induced myoclonus in Sprague‒Dawley rats involves the activation of neocortical Calpain-2 and its decrement on KCC2 protein [PDF]
BMC AnesthesiologyBackground Etomidate-induced myoclonus has become a pressing clinical problem with an incidence of 50–80%. The underlying mechanism involves neocortical glutamate accumulation and N-methyl-d-aspartate (NMDA) receptor activity.
Yan Feng +2 more
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Etomidate Improves Antitumor Immunity by Suppressing PD-L1 Expression in Hepatocellular Carcinoma CellsSummary [PDF]
Cellular and Molecular Gastroenterology and HepatologyBackground & Aims: Etomidate, a prevalent intravenous anesthetic agent, has been implicated in the attenuation of tumorigenesis. Our recent investigations elucidated its capacity to impede the malignant progression of hepatocellular carcinoma (HCC ...
Jiali Xu +11 more
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UPLC-MS/MS Method for Detection of Etomidate and Its Metabolite Etomidate Acid Quantity in Blood [PDF]
Fayixue Zazhi, 2023 Objective To establish a method for the simultaneous quantitative analysis of etomidate and its metabolite etomidate acid in blood, and to discuss its application value in actual cases.
Xing HAN, Xin LIU, Ming-luo DU, Ruo-lun XU, Jia-rong LI, Chao LIU, Wei-guo LIU
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Effects of etomidate use in ICU patients on ventilator therapy: a study of 12,526 patients in an open database from a single center [PDF]
Korean Journal of Anesthesiology, 2021 Background There is a debate regarding the safety of etomidate. We evaluated the effects of etomidate on mortality in a large cohort of critical care patients.
Ha Yeon Park +5 more
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Polymorphisms of pharmacogenetic candidate genes affect etomidate anesthesia susceptibility
Frontiers in Genetics, 2022 Purpose: Etomidate is widely used in general anesthesia and sedation, and significant individual differences are observed during anesthesia induction.
Lulin Ma +11 more
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Journal of Applied Pharmaceutical Research, 2022 Etomidate is a hypnotic drug used as an intravenous anaesthetic induction agent. Etomidate causes myoclonic movements in 50-80% patients after induction which makes it less desirable for induction.
Mukesh K Sunda +3 more
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Journal of Orthopedic and Spine Trauma, 2021 Background: Etomidate is an efficient general anesthetic associated with injection pain. Etomidate-Lipuro is its lipid emulsion, suggested to have less adverse effects. We aim to compare the injection pain of etomidate vs.
Alireza Saliminia, Niloofar Esfahanian
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