Hyperpolarization following activation of K+ channels by excitatory postsynaptic potentials [PDF]
We have postulated that an excitatory postsynaptic potential (e.p.s.p.) may open voltage-sensitive K+ (‘M’) channels1, in an appropriate depolarizing range, and that this could alter the e.p.s.p. waveform. Consequently, the fast e.p.s.p.
Tsuneo Tosaka+3 more
semanticscholar +5 more sources
ANALYSIS OF THE SLOW EXCITATORY POSTSYNAPTIC POTENTIAL IN BULLFROG SYMPATHETIC GANGLION CELLS
The ionic mechanism of the slow excitatory postsynaptic potential (slow EPSP), i.e. the muscarinic action of acetylcholine (ACh), was studied either by stimulating preganglionic nerves or by applying ACh in curarized sympathetic ganglion cells of ...
Kenji Kuba, K. Koketsu
semanticscholar +5 more sources
Recurrent excitatory postsynaptic potentials induced by synchronized fast cortical oscillations [PDF]
Gamma frequency (about 20-70 Hz) oscillations occur during novel sensory stimulation, with tight synchrony over distances of at least 7 mm. Synchronization in the visual system has been proposed to reflect coactivation of different parts of the visual ...
Miles A. Whittington+4 more
semanticscholar +5 more sources
A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis [PDF]
The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis and to neuronal cell death in models of excitotoxicity and traumatic ...
Brenna C. Fearey+7 more
doaj +2 more sources
Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: Distribution and pharmacology [PDF]
BACKGROUND & AIMS Adenosine triphosphate (ATP) acting at P2 receptors mediates some fast excitatory postsynaptic potentials (fEPSPs) in myenteric neurons of guinea pig ileum. The present studies investigate the distribution of purinergic fEPSPs along the
KJ LePard+2 more
openalex +2 more sources
Synaptic transmission at the inner hair cell (IHC) afferent synapse, the first synapse in the auditory pathway, is specialized for rapid and reliable signaling.
Eunyoung Yi+2 more
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A slow excitatory postsynaptic potential mediated by 5-HT2 receptors in nucleus prepositus hypoglossi [PDF]
Intracellular recordings were made from neurons of the nucleus prepositus hypoglossi in slices of guinea pig medulla. 5-HT (serotonin) caused a hyperpolarization followed by a late depolarization.
DH Bobker
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Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation. [PDF]
The original proposal that substance P is involved in the regulation of nociceptive information at the first sensory synapse in the spinal cord has been substantiated by a wide range of evidence, but definitive support has been lacking, due primarily to ...
Yves De Koninck, J.L. Henry
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Heterosynaptic Regulation of α2A-Adrenoceptors on Glutamate/GABA Release in the Prefrontal Cortex of Rats [PDF]
Background/Objectives: Norepinephrine (NE) plays a crucial role in modulating cognitive processes via α2A-adrenoceptors (α2A-ARs) within the prefrontal cortex (PFC), an essential brain region responsible for higher cognitive functions.
Yaru Wei+5 more
doaj +2 more sources
Cognitive impairment after traumatic brain injury is associated with reduced long-term depression of excitatory postsynaptic potential in the rat hippocampal dentate gyrus. [PDF]
Zhang BL+7 more
europepmc +2 more sources