Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons [PDF]
Proceedings of the National Academy of Sciences, 1998 The manner in which the thousands of synaptic inputs received by a pyramidal neuron are summed is critical both to our understanding of the computations that may be performed by single neurons and of the codes used by neurons to transmit information. Recent work on pyramidal cell dendrites has shown that subthreshold synaptic inputs are modulated by ...
Nathaniel N. Urban, German Barrionuevo
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Heterosynaptic Regulation of α2A-Adrenoceptors on Glutamate/GABA Release in the Prefrontal Cortex of Rats [PDF]
BiomedicinesBackground/Objectives: Norepinephrine (NE) plays a crucial role in modulating cognitive processes via α2A-adrenoceptors (α2A-ARs) within the prefrontal cortex (PFC), an essential brain region responsible for higher cognitive functions.
Yaru Wei +5 more
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Effect of Background Synaptic Activity on Excitatory-Postsynaptic Potential-Spike Coupling
, 2017 Neurons receive large amount of synaptic inputs in vivo, which may impact the coupling between EPSPs and spikes. We mimicked the in vivo synaptic activity of the cell with the dynamic clamp system. We recorded from pyramidal cells in neocortical slices in vitro to investigate how timing and probability of spike generation in response to an EPSP is ...
Veronika Zsiros
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Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: Distribution and pharmacology [PDF]
Gastroenterology, 1997 KJ LePard +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2002 Gaël Daoudal +2 more
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A Simple Mathematical Model of Second-Messenger Mediated Slow Excitatory Postsynaptic Potentials
Journal of Computational Neuroscience, 2000 We have developed a novel and simple mathematical model of a slow excitatory postsynaptic potential (EPSP) based on an abstraction of the processes of activation, inactivation, and summation of a cAMP, protein kinase A (PKA)-dependent second-messenger cascade.
Bertrand, P. P +3 more
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Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1991 Yves De Koninck, J.L. Henry
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An analysis of the action of pentobarbitone on the excitatory postsynaptic potentials and membrane properties of neurones in the guinea‐pig olfactory cortex [PDF]
British Journal of Pharmacology, 1986 Carl D. Richards, K. Strupinski
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Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex [PDF]
Journal of Integrative Neuroscience, 2020 Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects.
Jia Hui Wong, Faruque Reza, Sangu Muthuraju, Huei Gau Chuang, Jingli Zhang, Mohd Harizal Senik, Siti Rafidah Yusof, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Nor Hadiani Ismail, Jafri Malin Abdullah
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