Results 51 to 60 of about 371,477 (270)
Complex events initiated by individual spikes in the human cerebral cortex.
PLoS Biology, 2008 Synaptic interactions between neurons of the human cerebral cortex were not directly studied to date. We recorded the first dataset, to our knowledge, on the synaptic effect of identified human pyramidal cells on various types of postsynaptic neurons and
Gábor Molnár +8 more
doaj +1 more source
Frontiers in Neuroscience, 2020 Signaling from the synapse to nucleus is mediated by the integration and propagation of both membrane potential changes (postsynaptic potentials) and intracellular second messenger cascades.
Jian Fu +3 more
doaj +1 more source
Regulation of Irregular Neuronal Firing by Autaptic Transmission [PDF]
, 2016 The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons participates in the ...
Chen, Mingming +9 more
core +3 more sources
Nanodiamonds-induced effects on neuronal firing of mouse hippocampal microcircuits [PDF]
Scientific Reports 8, 2221 (2018), 2018 Fluorescent nanodiamonds (FND) are carbon-based nanomaterials that can efficiently incorporate optically active photoluminescent centers such as the nitrogen-vacancy complex, thus making them promising candidates as optical biolabels and drug-delivery agents. FNDs exhibit bright fluorescence without photobleaching combined with high uptake rate and low
arxiv +1 more source
Information processing occurs via critical avalanches in a model of the primary visual cortex [PDF]
J. Phys.: Conf. Ser. 686 012008 (2016), 2015 We study a new biologically motivated model for the Macaque monkey primary visual cortex which presents power-law avalanches after a visual stimulus. The signal propagates through all the layers of the model via avalanches that depend on network structure and synaptic parameter.
arxiv +1 more source
Synaptic potentiation of dual‐component excitatory postsynaptic currents in the rat hippocampus. [PDF]
The Journal of Physiology, 1995 1. Whole‐cell patch‐clamp recording has been used to study tetanus‐induced synaptic potentiation of dual‐component excitatory postsynaptic currents (EPSCs) in the CA1 region of rat hippocampal slices, following blockade of GABAA and GABAB receptor‐mediated synaptic inhibition. 2.
K A Clark, Graham L. Collingridge
openaire +3 more sources
Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]
, 1980 Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri +36 more
core +1 more source
Brain injury impairs working memory and prefrontal circuit function
Frontiers in Neurology, 2015 More than 2.5 million Americans suffer a traumatic brain injury (TBI) each year. Even mild to moderate traumatic brain injury causes long-lasting neurological effects.
Colin James Smith +5 more
doaj +1 more source
Exploring the role of NMDA receptor in memory
German Journal of Pharmaceuticals and Biomaterials, 2023 N-Methyl-D-aspartate (NMDA), a receptor belonging to the family of ionotropic glutamate receptors (iGluRs), plays various physiological and pathological roles in the central nervous system (CNS).
Pooja Tiwary +3 more
doaj +1 more source
A minimal model for synaptic integration in simple neurons [PDF]
Physica D 426 (2021) 132988, 2020 Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties of any given neuron. We study a simple model for the summation of excitatory inputs from synapses and illustrate its use by characterizing some functional properties of postsynaptic ...
arxiv +1 more source