Results 191 to 200 of about 90,697 (359)

Medication‐resistant epilepsy is associated with a unique gut microbiota signature

open access: yesEpilepsia, EarlyView.
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva   +14 more
wiley   +1 more source

NBQX Attenuates Excitotoxic Injury in Developing White Matter [PDF]

open access: hybrid, 2000
Pamela L. Follett   +3 more
openalex   +1 more source

The Insulin/IGF Signaling Regulator Cytohesin/GRP-1 Modulates Sensitivity to Excitotoxicity in C. elegans

open access: yes, 2015
Excitotoxicity is a form of neurodegeneration that serves as the main underlying cause of brain damage in stroke/brain ischemia, and a contributing factor in a range of neurological diseases such as Epilepsy, ALS, Alzheimer, and Huntington\u27s disease ...
Tehrani, Nazila
core  

A non‐redundant role of EAAT3 for ATP synthesis mediated by GDH in dopaminergic neuronal cells: a new avenue for glutamate metabolism and protection in Parkinson's disease

open access: yesThe FEBS Journal, EarlyView.
Parkinson's disease (PD) is a severe brain disorder caused by the loss of dopaminergic neurons. This study found that activating the enzyme glutamate dehydrogenase (GDH), by using the GDH activator BCH, protects cells and improves their energy production. It also highlights the previously undescribed role of EAAT3 in GDH‐dependent protection against PD
Alessandra Preziuso   +7 more
wiley   +1 more source

Role of Glutamate Receptor-Mediated Excitotoxicity in Bilirubin-Induced Brain Injury in the Gunn Rat Model

open access: hybrid, 1998
John W. McDonald   +3 more
openalex   +1 more source

d‐amino acids: new functional insights

open access: yesThe FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni   +5 more
wiley   +1 more source

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