TDP‐43Q331K mice exhibit altered proliferative dynamics in oligodendrocytes and their precursors. Oligodendroglial cell death is evident in TDP‐43Q331K mice. TDP‐43Q331K mice display altered myelin reflectance and pathology in the spinal cord. ABSTRACT Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the ...
Katherine N. Lewis +8 more
wiley +1 more source
Using human genomics to validate drug targets for acute ischemic stroke. [PDF]
Heitsch L, Lee JM.
europepmc +1 more source
NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia [PDF]
Araki, Toshiyuki +6 more
core +2 more sources
NP031112, a Thiadiazolidinone Compound, Prevents Inflammation and Neurodegeneration under Excitotoxic Conditions: Potential Therapeutic Role in Brain Disorders [PDF]
Rosario Luna‐Medina +6 more
openalex +1 more source
Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien +4 more
wiley +1 more source
Immunoexcitoxicity as the mechanism of CNS damage from COVID-19 "vaccinations". [PDF]
Blaylock RL.
europepmc +1 more source
Involvement of the GluN2A and GluN2B Subunits in Synaptic and Extrasynaptic N-methyl-d-aspartate Receptor Function and Neuronal Excitotoxicity [PDF]
Xianju Zhou +4 more
openalex +1 more source
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol +3 more
wiley +1 more source
Patterns of altered in vivo brain metabolism in patients with amyotrophic lateral sclerosis (ALS) and asymptomatic C9orf72 mutation carriers: a cross-sectional <sup>1</sup>H and <sup>31</sup>P magnetic resonance spectroscopic 7T imaging study. [PDF]
Westeneng HJ +12 more
europepmc +1 more source

