Results 1 to 10 of about 167,613 (264)

Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses [PDF]

Proc Natl Acad Sci U S A (20/10/2006) sous presse, 2006
Synaptic vesicle (SV) exocytosis mediating neurotransmitter release occurs spontaneously at low intraterminal calcium concentrations and is stimulated by a rise in intracellular calcium.
A. Scheuber, Blagoveshchenskaya, Dell'Angelica, Fa  ndez, G. Raposo, Goda, Guti  rrez, Hayashi, J.-C. Poncer, Kamiya, Kantheti, L. Danglot, Li, Lopantsev, Musleh, Muzerelle, R. Rudge, Rizzoli, Rosenmund, Sakaba, Schoch, Sj  str  m, Stobrawa, Stoppini, Sudhof, Sugita, Sugita, T. Binz, T. Galli, Takei, Vogt, Woodhall, Xu   +32 more
core   +7 more sources

Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells [PDF]

, 1990
Undifferentiated and differentiated HL-60 leukemic cells possess nucleotide receptors which functionally couple to phospholipase C via pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins).
Seifert, Roland, Wenzel-Seifert, Katharina   +1 more
core   +3 more sources

Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]

, 1990
The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Ahnert-Hilger, G., Dayanithi, G., Gratzl, Manfred, Nordmann, J. J., Weller, U.   +4 more
core   +6 more sources

Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells [PDF]

, 2016
open5noMost endocrine cells secrete hormones as a result of Ca(2+)-regulated exocytosis, i.e., fusion of the membranes of hormone-containing secretory granules with the cell membrane, which allows the hormone molecules to escape to the extracellular ...
Cortese, Giuliana, Montefusco, Francesco, Pedersen, Morten Gram, Riz, Michela, Tagliavini, Alessia   +4 more
core   +1 more source

Differential cargo mobilisation within Weibel-Palade bodies after transient fusion with the plasma membrane. [PDF]

, 2014
Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation ...
AE Cowan, AJ Cochilla, C Amatore, C Nanavati, C Soekmadji, D Perrais, D Reigada, DE Koppel, DE Koppel, EA Cookson, ER Weibel, G Zupancic, HL Zenner, I Hafez, I Kouranti, J Hartmann, J Hol, J Zimmerberg, JA Berriman, JB Manneville, JE Sadler, L Knipe, Laura Knipe, LJ Breckenridge, Ludger Johannes, M Braun, M Erent, M Weiss, Matthew J. Hannah, MG Rondaij, MJ Hannah, MJ Mourik, ML Kelly, N Vardjan, NI Kiskin, Nikolai I. Kiskin, P Verdugo, PE Marszalek, R Bierings, R Bierings, R Ghez, R Rahamimoff, RH Huang, S Obermuller, S Scepek, T Kishimoto, T Nemoto, TD Nightingale, TD Parsons, Tom Carter, V Babich, V Babich, Victor Babich   +52 more
core   +7 more sources

Millimolar concentrations of free magnesium enhance exocytosis from permeabilized rat pheochromocytoma (PC 12) cells [PDF]

, 1989
The role of Mg2+ during the final steps of exocytosis was investigated using rat pheochromocytoma cells (PC12) permeabilized with bacterial pore forming toxins.
Ahnert-Hilger, Ahnert-Hilger, Ahnert-Hilger, Ahnert-Hilger, Ahnert-Hilger, Ammann, Bader, Bhakdi, Bhakdi, Ekerdt, Flodgaard, Föhr, Gilman, Greene, Knight, Lind, Sillen, Simon   +17 more
core   +1 more source

The rab3A-22A chimera prevents sperm exocytosis by stabilizing open fusion pores [PDF]

, 2016
At the final stage of exocytotis, a fusion pore opens between the plasma and a secretory vesicle membranes; typically, when the pore dilates the vesicle releases its cargo.
Bustos, Matias Alberto, De la Iglesia, Paola X., Lucchesi, Ornella, Pocognoni, Cristián Adrián, Quevedo, María Florencia, Tomes, Claudia Nora   +5 more
core   +1 more source

CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]

, 2009
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Ackermann, Frauke, Boekhoff, Ingrid, Borth, Heike, Buech, Thomas, Gudermann, Thomas, Zitranski, Nele   +5 more
core   +1 more source

Ca2+-Stimulated Catecholamine Release from alpha-Toxin Permeabilized PC12 Cells [PDF]

, 1987
Two possible cellular pathways of catecholamines from the chromaffin vesicles of PC 12 cells to the surrounding medium are explored in this study. The direct one circumventing the cytoplasm can be activated in a-toxin-permeabilized cells with micromolar ...
Ahnert-Hilger, G., Bräutigam, M., Gratzl, Manfred   +2 more
core   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Baumert M., Bittner M. A., Bittner M. A., Bittner M. A., Blasi J., Elferink L. A., Fischer G., Geppert M., Halpern J. L., Hess S. D., Jahn R., MANFRED GRATZL, Marqueze-Pouey B., McMahon H. T., Schiavo G., Schiavo G., Schiavo G., Schmidle T., Shirataki H., Shoji-Kasai Y., Stecher B., Thomas L., Trimble W. S., Walch-Solimena C., Wright J. F., Yoshida A.   +28 more
core   +1 more source