Results 31 to 40 of about 167,613 (264)
Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes
bioRxiv, 2019 Glucagon is released from pancreatic α-cells to activate pathways that raise blood glucose. Its secretion is regulated by α-cell-intrinsic glucose sensing and paracrine control through insulin and somatostatin.
Muhmmad Omar-Hmeadi +4 more
semanticscholar +1 more source
Frontiers in Cellular Neuroscience, 2014 The soma of many neurons releases large amounts of transmitter molecules through an exocytosis process that continues for hundreds of seconds after the end of the triggering stimulus.
Carolina eLeon-Pinzon +4 more
doaj +1 more source
At the intersection of exocytosis and endocytosis in plants.
New Phytologist, 2019 Vesicle exocytosis and endocytosis control the activities and turnover of plasma membrane proteins required for signaling triggering or attenuating at the cell surface.
Liang Zhang, Jingjing Xing, Jinxing Lin
semanticscholar +1 more source
PLoS ONE, 2011 BackgroundWeibel-Palade bodies (WPB) are endothelial cell (EC) specific secretory organelles containing Von Willebrand factor (VWF). The temperature-dependence of Ca(2+)-driven WPB exocytosis is not known, although indirect evidence suggests that WPB ...
Lindsay Hewlett +6 more
doaj +1 more source
Multiscale modeling of exocytosis in the fertilization process [PDF]
J Phys Chem Biophys 4: 161 (2014), 2015 We discuss the implementation of a multiscale biophysico-chemical model able to cope with the main mechanisms underlying cumulative exocytosis in cells. The model is based on a diffusion equation in the presence of external forces that links calcium signaling and the biochemistry associated to the activity of cytoskeletal-based protein motors.
arxiv +1 more source
Enhancing the Study of Quantal Exocytotic Events: Combining Diamond Multi-Electrode Arrays with Amperometric PEak Analysis (APE) an Automated Analysis Code [PDF]
Biosensors. 2023; 13(12):1033, 2023 MicroGraphited-Diamond-Multi Electrode Arrays ({\mu}G-D-MEAs) can be successfully used to reveal, in real time, quantal exocytotic events occurring from many individual neurosecretory cells and/or from many neurons within a network. As {\mu}G-D-MEAs arrays are patterned with up to 16 sensing microelectrodes, each of them recording large amounts of data
arxiv +1 more source
Frontiers in Physiology, 2012 We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali eTrueta +1 more
doaj +1 more source
PLoS ONE, 2020 α-Klotho is a type 1 transmembrane protein that exhibits aging suppression function. The large amino-terminal extracellular domain of α-klotho is shed as soluble klotho (sKlotho) and functions as a circulating cardioprotective hormone.
Jian Xie +4 more
doaj +1 more source
A Novel Role of the TRPM4 Ion Channel in Exocytosis
Cells, 2022 Under physiological conditions, the widely expressed calcium-activated TRPM4 channel conducts sodium into cells. This sodium influx depolarizes the plasma membrane and reduces the driving force for calcium entry.
Paulina Stokłosa +2 more
doaj +1 more source
Geometry aware predictive models for exocytosis [PDF]
arXiv, 2023 Inter neuron communication happens through the exchange of neurotransmitters at the synapse by a process known as exocytosis. This makes exocytosis a fundamental process of information exchange in the body. The exocytosis process has a distinct geometry as it involves a vesicle that attaches to the cell membrane and then releases the neurotransmitters ...
arxiv