The Specificity of Transgene Suppression in Plants by Exogenous dsRNA [PDF]
Plants, 2022 The phenomenon of RNA interference (RNAi) is widely used to develop new approaches for crop improvement and plant protection. Recent investigations show that it is possible to downregulate plant transgenes, as more prone sequences to silencing than ...
Konstantin V. Kiselev +5 more
doaj +6 more sources
Recent Advances in the Development of Exogenous dsRNA for the Induction of RNA Interference in Cancer Therapy [PDF]
Molecules, 2021 Selective regulation of gene expression by means of RNA interference has revolutionized molecular biology. This approach is not only used in fundamental studies on the roles of particular genes in the functioning of various organisms, but also possesses ...
Tatiana S. Golubeva +2 more
doaj +7 more sources
Exogenous dsRNA-Mediated RNAi: Mechanisms, Applications, Delivery Methods and Challenges in the Induction of Viral Disease Resistance in Plants [PDF]
VirusesThe increasing challenges posed by plant viral diseases demand innovative and sustainable management strategies to minimize agricultural losses. Exogenous double-stranded RNA (dsRNA)-mediated RNA interference (RNAi) represents a transformative approach ...
Emmadi Venu +8 more
doaj +6 more sources
Multiple dsRNases Involved in Exogenous dsRNA Degradation of Fall Armyworm Spodoptera frugiperda [PDF]
Frontiers in Physiology, 2022 RNAi is regarded as a promising technology for pest control. However, not all insects are sensitive to RNAi. Studies have confirmed that insect dsRNases are one of key factors affecting RNAi efficiency.
Yang Yao +7 more
doaj +4 more sources
Impact of Exogenous dsRNA on miRNA Composition in Arabidopsis thaliana [PDF]
PlantsThe application of double-stranded RNAs (dsRNAs) to plant surfaces has emerged as a promising tool for manipulating gene expression in plants and pathogens, offering new opportunities for crop improvement.
Nikolay N. Nityagovsky +3 more
doaj +4 more sources
Silencing of the Nicotiana benthamiana phytoendesaturase gene by root treatment of exogenous dsRNA [PDF]
Вавиловский журнал генетики и селекцииRNA interference (RNAi) is a powerful tool for gene silencing. It has recently been used to design promising plant protection strategies against pests such as viruses, insects, etc.
T. S. Golubeva +5 more
doaj +2 more sources
Inhibition of Hop Stunt Viroid by Exogenous Double-Stranded RNA in Micropropagated Grapevine Plantlets [PDF]
The Plant Pathology JournalHop stunt viroid (HSVd) infection reduces grapevine (Vitis vinifera) yield and quality, leading to significant economic losses. Conventional methods for producing virus-free plantlets often fail to completely eliminate viroids, necessitating alternative ...
Chae-Min Kang, Rae-Dong Jeong
doaj +2 more sources
BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses [PDF]
Advanced ScienceTomato viral diseases severely restrict the safe and efficient tomato production, and current control methods are lacking. Therefore, the development of green and efficacious biopesticides is imperative.
Xuedong Liu +7 more
doaj +2 more sources
Spray-induced gene silencing enables the characterization of gene function during pre-penetration stages in Blumeria graminis f. sp. tritici [PDF]
Frontiers in Plant ScienceBlumeria graminis f. sp. tritici (Bgt), the causal agent of wheat powdery mildew, poses a significant threat to global wheat production. As an obligate biotroph, Bgt is recalcitrant to stable genetic manipulation. Although host-induced gene silencing has
Meihui Zhang +11 more
doaj +2 more sources
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response [PDF]
, 2012 Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-?, influences interferon (IFN) production by primary
Amanda Tatler +10 more
core +18 more sources