The influence of exoribonucleases in the regulation of stress related small RNAs [PDF]
, 2015 De modo a poder colonizar um ser humano, a bactéria Escherichia coli tem de ser capaz de resistir tanto a condições de anaerobiose como a um pH de 2.
BRAVO, Afonso Martins
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Structural and catalytic diversity of coronavirus proofreading exoribonuclease
Nature CommunicationsAbstract The coronavirus proofreading exoribonuclease (ExoN) is essential for genome fidelity and immune evasion of the viruses. Despite its critical roles in the viral life cycle, it is unclear how ExoNs across different coronaviruses diverge in their structures and catalytic properties, which may lead to differences in viral genome ...
Yu Li +4 more
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Three models explaining indirect stabilizing effects of TbRND depletion on mRNAs in a KPAP1-depleted background. [PDF]
, 2012 A. TbRND recruits exoribonucleases to nonadenylated transcripts. B. Upon TbRND/KPAP1 co-depletion, RNAs that are normally targets of TbRND build up and generally dilute the effects of mitochondrial ribonucleases on other transcripts, thus stabilizing ...
Laurie K. Read (163144) +3 more
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Molecular and developmental analysis of non-coding RNA metabolism in" C. elegans" : the exoribonuclease XRN2 and the RNA- binding proteins SART-3 and USIP-1 [PDF]
, 2014 About three quarters of a eukaryotic genome are transcribed into RNA. However, only
Rüegger, Stefan
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3' To 5' Exoribonucleases In Arabidopsis Thaliana Plastids [PDF]
, 2012 Chloroplast genes and metabolic activities are regulated by the products of nuclear genes, acting mostly at the post-transcriptional level. Polynucleotide phosphorylase (PNP) and Ribonuclease R (RNR1) are the two known nucleus-encoded exoribonucleases ...
Germain, Arnaud
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RNase R vs. PNPase: selecting the best-suited exoribonuclease for environmental adaptation [PDF]
3' → 5' exoribonucleases play a critical role in many aspects of RNA metabolism. RNase R, PNPase, and RNase II are the major contributors to RNA processing, maturation, and quality control in bacteria.
Pavankumar, Theetha L
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Purification of a human polyribosome-associated 3‘ to 5‘ exoribonuclease.
Journal of Biological Chemistry, 1994 In cells and cell-free extracts, the early steps in histone mRNA decay occur at the 3' terminus and appear to be catalyzed by a polysome-associated 3' to 5' exoribonuclease. We describe the purification of a polysomal 3' to 5' exoribonuclease that is magnesium-dependent, active at pH 7-8 in salt concentrations below 200 mM, and resistant to the ...
N, Caruccio, J, Ross
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RNA helicases in RNA decay [PDF]
, 2018 RNA molecules have the tendency to fold into complex structures or to associate with complementary RNAs that exoribonucleases have difficulties processing or degrading.
Vanessa Khemici +3 more
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Escherichia coli exoribonuclease T: Structure, function and mechanism of action [PDF]
, 2002 Exoribonuclease T (RNase T) is one of eight distinct 3 ' to 5' exoribonucleases present in Escherichia coli. It plays an important role in stable RNA metabolism, including tRNA end turnover and 3' maturation of many stable RNAs.
Zuo, Yuhong
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Xrn1 Exoribonuclease—An Intrinsic Marker of Yeast Population Growth
Frontiers in Bioscience-EliteBackground: Xrn1 exoribonuclease is the major mRNA degradation enzyme in Saccharomyces cerevisiae. In exponentially growing cells, Xrn1 is localised in the yeast cells and directs the degradation of mRNA molecules. Xrn1 is gradually deposited and presumably inactivated in the processing bodies (P-bodies) as the yeast population ages.
Tomas Vomastek, Tomas Grousl
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