Shared properties and singularities of exoribonuclease-resistant RNAs in viruses
What viral RNA genomes lack in size, they make up for in intricacy. Elaborate RNA structures embedded in viral genomes can hijack essential cellular mechanisms aiding virus propagation.
Quentin Vicens, Jeffrey S. Kieft
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Elastic Coupling Between RNA Degradation and Unwinding by an Exoribonuclease [PDF]
Loading a Spring To regulate cellular RNA levels, transcription must be balanced by RNA degradation. An important player is the exosome, which can unwind and degrade structured RNA. Lee et al. (p.
Gwangrog Lee+4 more
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Exoribonuclease RNase R protects Antarctic Pseudomonas syringae Lz4W from DNA damage and oxidative stress. [PDF]
Mittal P+7 more
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Identification of a novel deFADding activity in human, yeast and bacterial 5' to 3' exoribonucleases. [PDF]
Identification of metabolite caps including FAD on the 5′ end of RNA has uncovered a previously unforeseen intersection between cellular metabolism and gene expression.
Sharma S+5 more
europepmc +2 more sources
Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay. [PDF]
Hernández S+15 more
europepmc +2 more sources
The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease [PDF]
DIS3 is a conserved exoribonuclease and catalytic subunit of the exosome, a protein complex involved in the 3’ to 5’ degradation and processing of both nuclear and cytoplasmic RNA species.
Sophie Robinson+3 more
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The Phosphorolytic Exoribonucleases Polynucleotide Phosphorylase and RNase PH Stabilize sRNAs and Facilitate Regulation of Their mRNA Targets [PDF]
Todd A. Cameron, Nicholas R. De Lay
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Structural characterization of NrnC identifies unifying features of dinucleases
RNA degradation is fundamental for cellular homeostasis. The process is carried out by various classes of endolytic and exolytic enzymes that together degrade an RNA polymer to mono-ribonucleotides.
Justin D Lormand+8 more
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Regulation of miRNA content. Part 2. Degradation of miRNAs
The scientific review presents the process of regulation of microRNA content — microRNA degradation. To write the article, information was searched using databases Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The ...
A.E. Abaturov, V.L. Babуch
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Promiscuous exoribonucleases of Escherichia coli [PDF]
M. Deutscher
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