Results 31 to 40 of about 202,955 (306)
Therapeutic Advances of Stem Cell-Derived Extracellular Vesicles in Regenerative Medicine
Cells, 2020 Extracellular vesicles (EVs), which are the main paracrine components of stem cells, mimic the regenerative capacity of these cells. Stem cell-derived EVs (SC-EVs) have been used for the treatment of various forms of tissue injury in preclinical trials ...
Lei Yin +8 more
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Frontiers in Oncology, 2020 Neutrophils are prominent components of solid tumors and exhibit distinct phenotypes in different tumor milieu. We have previously shown that tumor extracellular vesicles (EVs) could induce pro-tumor activation of neutrophils; however, the role of tumor ...
Yinghong Shi +19 more
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Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine
Cells, 2021 Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that are then released into the extracellular space through a merging of the multivesicular body with the plasma membrane.
Mangesh D Hade, Caitlin N Suire, Z. Suo
semanticscholar +1 more source
Cells, 2021 Cancer multidrug resistance (MDR) is one of the main challenges for cancer treatment efficacy. MDR is a phenomenon by which tumor cells become resistant to several unrelated drugs.
Diana Sousa +7 more
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The Scientific World JOURNAL, 2009 Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responsesin vivo.
Irena Dimov +2 more
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Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells [PDF]
, 2019 BACKGROUND: The pathology of juvenile dermatomyositis (JDM) is characterized by prominent vessel wall and perivascular inflammation. This feature of the disease has remained unexplained and under-investigated. We have hypothesized that plasma exosomes,
Chen, Yanmin +6 more
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Extracellular vesicles: Exosomes, microvesicles, and friends
Journal of Cell Biology, 2013 Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively.
G. Raposo, W. Stoorvogel
semanticscholar +1 more source
, 2010 We describe the events surrounding the identification of the exosome complex and the subsequent early development of the field. Like many scientific discoveries, the initial identification and characterization ofthe exosome was based on a combination of skill, good fortune--and the availability of cutting edge technology.
Phil Mitchell, David Tollervey
openaire +4 more sources
Journal of the American Society of Nephrology, 2015 Acute kidney injury, AKI, is relatively common in the hospital setting, and beyond the identification of the underlying cause and supportive measures, little can be done to facilitate healing of the compromised kidney.
Christopher J. Ward +1 more
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Stem Cell Research & Therapy, 2022 Background Mesenchymal stromal cells (MSCs) and their extracellular vesicles (MSC-EVs) have demonstrated to elicit immunomodulatory and pro-regenerative properties that are beneficial for the treatment of chronic wounds.
Kevin Las Heras +6 more
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