Results 31 to 40 of about 202,629 (353)
Assessing the role of surface glycans of extracellular vesicles on cellular uptake
Scientific Reports, 2019 Extracellular vesicles (EVs) are important mediators of cell-cell communication in a broad variety of physiological contexts. However, there is ambiguity around the fundamental mechanisms by which these effects are transduced, particularly in relation to
Charles Williams +8 more
doaj +1 more source
Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]
, 2016 Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne +3 more
core +1 more source
Heliyon, 2023 Objectives: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic ...
Yuji Nakamachi +7 more
doaj +1 more source
Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. [PDF]
, 2020 Exosomes are nanovesicles secreted by virtually all cells. Exosomes mediate the horizontal transfer of various macromolecules previously believed to be cell-autonomous in nature, including nonsecretory proteins, various classes of RNA, metabolites, and ...
Anderson, Johnathon D +3 more
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Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]
, 2019 Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C +4 more
core +2 more sources
Artificial exosomes for translational nanomedicine
Journal of Nanobiotechnology, 2021 Exosomes are lipid bilayer membrane vesicles and are emerging as competent nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges such as massive production, standard isolation, drug loading, stability and quality ...
Yong-Jiang Li +7 more
doaj +1 more source
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]
, 2018 Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C. +23 more
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Cell Infectivity in relation to bovine leukemia virus gp51 and p24 in bovine milk exosomes. [PDF]
PLoS ONE, 2013 Exosomes are small membranous microvesicles (40-100 nm in diameter) and are extracellularly released from a wide variety of cells. Exosomes contain microRNA, mRNA, and cellular proteins, which are delivered into recipient cells via these exosomes, and ...
Tetsuya Yamada +3 more
doaj +1 more source
Exosomes: Diagnostic and Therapeutic Implications in Cancer
Pharmaceutics, 2023 Exosomes are a subset of extracellular vesicles produced by all cells, and they are present in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune suppression, immune surveillance, metabolic reprogramming ...
Hyein Jo, Kyeonghee Shim, Dooil Jeoung
doaj +1 more source
Extracellular vesicles, ageing, and therapeutic interventions [PDF]
, 2018 A more comprehensive understanding of the human ageing process is required to help mitigate the increasing burden of age-related morbidities in a rapidly growing global demographic of elderly individuals.
Neytchev, Ognian +3 more
core +1 more source