Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Nature Network Boston, 2012 Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects.
H. Peinado +24 more
semanticscholar +1 more source
Exosomes: Versatile Nano Mediators of Immune Regulation. [PDF]
, 2019 One of many types of extracellular vesicles (EVs), exosomes are nanovesicle structures that are released by almost all living cells that can perform a wide range of critical biological functions.
Cacalano, Nicholas A +4 more
core +1 more source
Emerging Exosomes and Exosomal MiRNAs in Spinal Cord Injury [PDF]
Frontiers in Cell and Developmental Biology, 2021 Acute spinal cord injury (SCI) is a serious traumatic event to the spinal cord with considerable morbidity and mortality. This injury leads to short- and long-term variations in the spinal cord, and can have a serious effect on the patient’s sensory, motor, or autonomic functions.
Zhihan Zhu +5 more
openaire +4 more sources
Exosomes are natural carriers of exogenous siRNA to human cells in vitro [PDF]
, 2013 © 2013 Shtam et al. Background: Exosomes are nano-sized vesicles of endocytic origin that are involved in cell-to-cell communication including shuttle RNA, mainly mRNA and microRNA.
Filatov, MV +5 more
core +1 more source
Assessing the role of surface glycans of extracellular vesicles on cellular uptake
Scientific Reports, 2019 Extracellular vesicles (EVs) are important mediators of cell-cell communication in a broad variety of physiological contexts. However, there is ambiguity around the fundamental mechanisms by which these effects are transduced, particularly in relation to
Charles Williams +8 more
doaj +1 more source
Mechanical characterization of cells and microspheres sorted by acoustophoresis with in-line resistive pulse sensing [PDF]
Phys. Rev. Applied 13, 034058 (2020), 2019 Resistive Pulse Sensing (RPS) is a key label-free technology to measure particles and single-cell size distribution. As a growing corpus of evidence supports that cancer cells exhibit distinct mechanical phenotypes from healthy cells, expanding the method from size to mechanical sensing could represent a pertinent and innovative tool for cancer ...
arxiv +1 more source
Exosomes: key players in cancer and potential therapeutic strategy
Signal Transduction and Targeted Therapy, 2020 Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in intercellular communication. The components of exosomes, including proteins, DNA, mRNA, microRNA, long noncoding RNA, circular RNA, etc., which play a crucial role ...
J. Dai +9 more
semanticscholar +1 more source
Cell Infectivity in relation to bovine leukemia virus gp51 and p24 in bovine milk exosomes. [PDF]
PLoS ONE, 2013 Exosomes are small membranous microvesicles (40-100 nm in diameter) and are extracellularly released from a wide variety of cells. Exosomes contain microRNA, mRNA, and cellular proteins, which are delivered into recipient cells via these exosomes, and ...
Tetsuya Yamada +3 more
doaj +1 more source
Ultrasound-based Control of Micro-Bubbles for Exosome Delivery in Treating COVID-19 Lung Damage [PDF]
arXiv, 2021 The recent COVID-19 pandemic has resulted in high fatality rates, especially for patients who suffer from underlying health issues. One of the more serious symptoms exhibited from patients suffering from an acute COVID-19 infection is breathing difficulties and shortness of breath, which is largely due to the excessive fluid (cellular leakage and ...
arxiv
A Label-Free Platform for Identification of Exosomes from Different Sources. [PDF]
, 2019 Exosomes contain cell- and cell-state-specific cargos of proteins, lipids, and nucleic acids and play significant roles in cell signaling and cell-cell communication.
Bitan, Gal +7 more
core +2 more sources