Results 71 to 80 of about 222,944 (406)
Two pathways within endosomes use specific protein complexes or membrane domains to direct cargo for degradation or secretion from cells.
Marsh, M., van Meer, G.
openaire +4 more sources
Exosomes in lung cancer metastasis, diagnosis, and immunologically relevant advances
Lung cancer is a chronic wasting disease with insidious onset and long treatment cycle. Exosomes are specialized extracellular vesicles, at first exosomes were considered as a transporter of cellular metabolic wastes, but recently many studies have ...
Jianhua Zhao+4 more
doaj +1 more source
Antibody-loading of biological nanocarrier vesicles derived from red-blood-cell membranes [PDF]
Antibodies, disruptive potent therapeutic agents against pharmacological targets, face a barrier crossing immune-system and cellular-membranes. To overcome these, various strategies have been explored including shuttling via liposomes or bio-camouflaged nanoparticles.
arxiv
Plasmonic nano-aperture label-free imaging [PDF]
Label-free observation of nanoparticles by far-field optical microscopy is challenging because their ability to scatter or absorb light dramatically diminishes with decreasing size. Surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) imaging have shown promises and respective limitations.
arxiv +1 more source
Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda+15 more
core +3 more sources
Exosomes and exosomal miRNAs in cardiovascular protection and repair [PDF]
Cell-cell communication between cardiac and vascular cells and from stem and progenitor cells to differentiated cardiovascular cells is both an important and complex process, achieved through a diversity of mechanisms that have an impact on cardiovascular biology, disease and therapeutics.
Emanueli, Costanza+3 more
openaire +4 more sources
Artesunate (ATS) is considered the most widely employed artemisnin derivative in the treatment of Plasmodium falciparum malaria. However, poor solubility and low bioavailability of ATS limit its further clinical application.
Da Wang+12 more
doaj +1 more source
Glioblastoma-Derived Exosomes as Nanopharmaceutics for Improved Glioma Treatment
The use of cancer-derived exosomes has been studied in several cancer types, but the cancer-targeting efficacy of glioma-derived exosomes has not been investigated in depth for malignant glioblastoma (GBM) cells. In this study, exosomes were derived from
Hyeji Lee+7 more
doaj +1 more source
Proposal of Absolute Nanometer Size Measurement in Flow Cytometry Based on Laser Interferometry [PDF]
The author discusses the laser interference method to measure the size of small bio-particles: extracellular vesicles (EVs), exosomes and viruses of nanometer scale in flow cytometry. By introducing a new laser configuration in place of conventional optical system of the flow cytometry, the interference fringe (periodic intensity modulation) is created
arxiv
Application of exosomes as liquid biopsy in clinical diagnosis
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small extracellular vesicles with sizes between 30–150 nm.
Biting Zhou+7 more
semanticscholar +1 more source