Phylogenomic analysis of the collagen-like BclA proteins in Clostridioides difficile [PDF]
Applied and Environmental MicrobiologyClostridioides difficile is a Gram-positive, anaerobic, spore-forming bacterium and a major nosocomial pathogen, notable for its high genetic diversity. C.
Francisca Cid-Rojas +5 more
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The
mSphere, 2020 Clostridioides difficile is an obligately anaerobic, spore-forming, Gram-positive pathogenic bacterium that is considered the leading cause of nosocomial diarrhea worldwide.
A. Romero-Rodríguez +3 more
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Endospore appendages enhance adhesion of Bacillus cereus sensu lato spores to industrial surfaces, modulated by physicochemical factors [PDF]
Applied and Environmental MicrobiologySpores of species belonging to the Bacillus cereus sensu lato (s.l.) group are common contaminants in food processing environments due to their ability to adhere to surfaces and resist cleaning procedures.
Unni Lise Albertsdottir Jonsmoen +5 more
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Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores [PDF]
Anaerobe, 2021 Fidaxomicin has novel pharmacologic effects on C. difficile spore formation including outgrowth inhibition and persistent spore attachment. However, the mechanism of fidaxomicin attachment on spores has not undergone rigorous microscopic studies.Fidaxomicin attachment to C. difficile spores of three distinct ribotypes and C.
Eugénie Bassères +9 more
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Reliable delineation of Clostridioides difficile and related members of the family Peptostreptococcaceae using phylogenomics and spore coat protein-specific molecular markers [PDF]
Microbiology SpectrumTraditional bacterial classification relies on phenotypic traits (e.g., morphology and metabolic profiles), but these methods lack resolution for closely related taxa and are biased by culture conditions.
Jianying Han +4 more
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Ultrastructural Variability of the Exosporium Layer of Clostridium difficile Spores [PDF]
Applied and Environmental Microbiology, 2016 ABSTRACT The anaerobic sporeformer Clostridium difficile is the leading cause of nosocomial antibiotic-associated diarrhea in developed and developing countries. The metabolically dormant spore form is considered the transmission, infectious, and persistent morphotype, and the outermost exosporium layer is
Marjorie, Pizarro-Guajardo +4 more
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Beyond the spore, the exosporium sugar anthrose impacts vegetative Bacillus anthracis gene regulation in cis and trans [PDF]
Scientific Reports, 2023 The Bacillus anthracis exosporium nap is the outermost portion of spore that interacts with the environment and host systems. Changes to this layer have the potential to impact wide-ranging physiological and immunological processes.
Michael H. Norris +7 more
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Localization and Assembly of the Novel Exosporium Protein BetA of Bacillus anthracis [PDF]
Journal of Bacteriology, 2011 ABSTRACT The exosporium of Bacillus anthracis is comprised of two distinct layers: a basal layer and a hair-like nap that covers the basal layer. The hair-like nap contains the glycoproteins BclA and, most likely, BclB.
Brian M, Thompson +3 more
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The exosporium of Bacillus megaterium QM B1551 is permeable to the Red Fluorescence Protein of the coral Discosoma sp [PDF]
Frontiers in Microbiology, 2016 Bacterial spores spontaneously interact and tightly bind heterologous proteins. A variety of antigens and enzymes have been efficiently displayed on spores of Bacillus subtilis, the model system for spore formers. Adsorption on B.
Mariamichela Lanzilli +8 more
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Exosporium Morphogenesis in Bacillus Cereus and Bacillus Anthracis [PDF]
, 2010 A thesis presented to the faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of ...
Bellinzona, Monica Maria Fazzini
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