Results 31 to 40 of about 595 (145)

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

PLoS Pathogens, 2023
A genomic signature for endosporulation includes a gene coding for a protease, YabG, which in the model organism Bacillus subtilis is involved in assembly of the spore coat.
Eleonora Marini, Carmen Olivença, Sara Ramalhete, Andrea Martinez Aguirre, Patrick Ingle, Manuel N Melo, Wilson Antunes, Nigel P Minton, Guillem Hernandez, Tiago N Cordeiro, Joseph A Sorg, Mónica Serrano, Adriano O Henriques   +12 more
doaj   +1 more source

Assembly of the BclB glycoprotein into the exosporium and evidence for its role in the formation of the exosporium ‘cap’ structure in Bacillus anthracis [PDF]

Molecular Microbiology, 2012
SummaryThe outermost layer of the Bacillus anthracis spore consists of an exosporium comprised of an outer hair‐like nap layer and an internal basal layer. A major component of the hair‐like nap is the glycosylated collagen‐like protein BclA. A second collagen‐like protein, BclB, is also present in the exosporium.
Brian M, Thompson, Bryce C, Hoelscher, Adam, Driks, George C, Stewart   +3 more
openaire   +2 more sources

Architecture and Self-Assembly of Clostridium sporogenes and Clostridium botulinum Spore Surfaces Illustrate a General Protective Strategy across Spore Formers

mSphere, 2020
Spores, the infectious agents of many Firmicutes, are remarkably resilient cell forms. Even distant relatives can have similar spore architectures although some display unique features; they all incorporate protective proteinaceous envelopes.
Thamarai K. Janganan, Nic Mullin, Ainhoa Dafis-Sagarmendi, Jason Brunt, Svetomir B. Tzokov, Sandra Stringer, Anne Moir, Roy R. Chaudhuri, Robert P. Fagan, Jamie K. Hobbs, Per A. Bullough   +10 more
doaj   +3 more sources

Inhibition of spores to prevent the recurrence of Clostridioides difficile infection - A possibility or an improbability?

Journal of Microbiology, Immunology and Infection, 2021
Clostridioides difficile is one of the most common nosocomial gastrointestinal pathogens, and recurrence is a problematic issue because approximately 20–30% of patients experience at least one episode of recurrence, even after treatment with a ...
Chun-Wei Chiu, Pei-Jane Tsai, Ching-Chi Lee, Wen-Chien Ko, Yuan-Pin Hung   +4 more
doaj   +1 more source

The Morphology and Ultrastructure of the Spore and Exosporium of Some Clostridium Species [PDF]

Journal of General Microbiology, 1967
Surmmary The spores of original isolates of Clostridium species obtained from fresh and processed marine fish and from marine bottom deposits were compared with the spores of culture collection strains of the same species. These strains were Clostridium botulinum type E, C. sporogenes, C. bifermentans and C. sordellii.
W, Hodgkiss, Z J, Ordal, D C, Cann
openaire   +2 more sources

Beyond the spore, the exosporium sugar anthrose impacts vegetative Bacillus anthracis gene regulation in cis and trans

Scientific Reports, 2023
The Bacillus anthracis exosporium nap is the outermost portion of spore that interacts with the environment and host systems. Changes to this layer have the potential to impact wide-ranging physiological and immunological processes.
Michael H. Norris, Andrew P. Bluhm, Morgan C. Metrailer, Treenate Jiranantasak, Alexander Kirpich, Ted Hadfield, Jose Miguel Ponciano, Jason K. Blackburn   +7 more
doaj   +1 more source

ULTRASTRUCTURE OF THE EXOSPORIUM ENVELOPING SPORES OFBACILLUS CEREUS [PDF]

Journal of Bacteriology, 1964
Gerhardt, Philipp(The University of Michigan, Ann Arbor),and Edgar Ribi. Ultrastructure of the exosporium enveloping spores ofBacillus cereus. J. Bacteriol.88:1774–1789. 1964.—Structural details in the outer envelope of spores, such as those ofBacillus cereusandB.
P, GERHARDT, E, RIBI
openaire   +2 more sources

Characterization of the adherence of Clostridium difficile spores: The integrity of the outermost layer affects adherence properties of spores of the epidemic strain R20291 to components of the intestinal mucosa.

Frontiers in Cellular and Infection Microbiology, 2016
Clostridium difficile is the causative agent of the most frequently reported nosocomial diarrhea worldwide. The high incidence of recurrent infection is the main clinical challenge of C. difficile infections (CDI). Formation of C. difficile spores of the
Paola Mora-Uribe, Camila Miranda-Cardenas, Pablo Castro-Cordova, Fernando Gil, Iván Calderón, Juan Fuentes, Paula I. Rodas, Saeed Banawas, Mahfuzur R Sarker, Daniel Paredes-Sabja   +9 more
doaj   +1 more source

Synthesis of the Exosporium During Sporulation of Bacillus cereus [PDF]

Microbiology, 1984
Summary: Techniques of antigenic analysis were used to examine the synthesis of the exosporium during sporulation of Bacillus cereus. An antiserum to a soluble extract of exosporium from mature spores was used to analyse extracts of cells from various stages of the Bacillus life cycle by the technique of one-dimensional immunoelectrophoresis ...
J. P. Desrosier, J. C. Lara
openaire   +1 more source

Structural Characterization of Clostridium sordellii Spores of Diverse Human, Animal, and Environmental Origin and Comparison to Clostridium difficile Spores

mSphere, 2017
Clostridium sordellii is an often-lethal bacterium causing human and animal disease. Crucial to the infectious cycle of C. sordellii is its ability to produce spores, which can germinate into toxin-producing vegetative bacteria under favorable conditions.
Rebecca Rabi, Lynne Turnbull, Cynthia B. Whitchurch, Milena Awad, Dena Lyras   +4 more
doaj   +1 more source