Results 71 to 80 of about 113,929,087 (168)

Functional Characterization of Streptococcal Pyrogenic Exotoxin J, a Novel Superantigen

open access: yes, 2001
Streptococcal toxic shock syndrome (STSS) is a highly lethal, acute-onset illness that is a subset of invasive streptococcal disease. The majority of clinical STSS cases have been associated with the pyrogenic toxin superantigens (PTSAgs) streptococcal ...
John K. McCormick   +4 more
core   +1 more source

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 10, Page 2211-2222, October 2026.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco   +5 more
wiley   +1 more source

Analytical and preparative methods for β-exotoxin from Bacillus Thuringensis

open access: yes, 1987
Theβ-exotoxin fromBacillus thuringensis is a well known insecticide. The bioassay usually employed for its analysis is time-consuming and subject to many disturbances. The previously reported HPLC analysis has been shown to give erroneous results in some
Kärppä, Pirkko   +2 more
core   +1 more source

Obtaining the recombinant fusion protein OprF-aTox of Pseudomonas aeruginosa whith protective properties

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
Into the cells of Escherichia coli (strain BL21(DE3)) two forms of the fusion protein Pseudomonas aeruginosa containing the full length outer membrane protein F (OprF) and nontoxic form of Exotoxin A (without 106 C-terminal amino acid residues) have been
A. V. Soldatenkova   +4 more
doaj  

Anthrax protective antigen is a calcium-dependent serine protease

open access: yesVirulence, 2018
Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor.
Lisanne Storm   +7 more
doaj   +1 more source

Superantigens in Cancer Immunotherapy: Mechanisms, Engineering Strategies, and Therapeutic Potential

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Schematic overview of superantigen‐mediated antitumor immune responses and immune suppression within the tumor microenvironment. (1) Antigen‐presenting cells activate T cells through MHC‐II/TCR interactions resulting in the production of cytokines (2) The pro‐inflammatory cytokines released by activated immune cells stimulate downstream immune ...
Urooj Yousaf Virk   +5 more
wiley   +1 more source

Features of exotoxin production of vaccine strains of anthrax pathogen for use in the veterinary industry

open access: yesUkrainian Journal of Veterinary Sciences
Exotoxins that produce vaccine strains of the anthrax pathogen are the main source of immunogenicity of anti-selective vaccines used in veterinary medicine.
H. Zaviriukha   +4 more
doaj   +1 more source

Plant‐Derived Nanoparticles (PDNPs) in Food Safety and Preservation: Pros and Cons

open access: yeseFood, Volume 7, Issue 4, August 2026.
Plant‐derived nanoparticles (PDNPs) synthesized via green methods demonstrate antimicrobial, antioxidant, barrier, eco‐friendly, and cost‐effective properties, while facing challenges in large‐scale production, synthesis standardization, and absence of specific food safety regulations. ABSTRACT Ensuring food safety and extending shelf life across fresh
Md. Shakil Ahmed   +2 more
wiley   +1 more source

Exotoxin A stimulates fluid reabsorption from distal airspaces of lung in anesthetized rats

open access: yes, 1996
To determine whether exotoxin A may affect the transport of fluid across the lung epithelium, two isogenic strains of Pseudomonas aeruginosa PA103 (10(8) colony-forming units), one (PA103 tox omega) with a structural gene mutation in exotoxin A, were ...
J. F. Pittet   +5 more
core   +1 more source

Determining Induction Conditions for Expression of Truncated Diphtheria Toxin and Pseudomonas Exotoxin A in E. coli BL21

open access: yesNovelty in Biomedicine, 2018
Background: Targeted cancer therapies have played a great role in the treatment of malignant tumors, in the recent years. Among these therapies, targeted toxin therapies such as immunotoxins, has improved the patient’s survival rate by minimizing the ...
Sahel Amoozadeh   +4 more
doaj   +1 more source

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